CRCGN014_HEPG2_24H:L21 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_24H:L21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.29828
|
|
PARP1
|
poly (ADP-ribose) polymerase 1
|
4.85392
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.55257
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.16641
|
|
UBQLN2
|
ubiquilin 2
|
4.10677
|
|
LCN2
|
lipocalin 2
|
3.9903
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
3.96363
|
|
FBXO7
|
F-box protein 7
|
3.69268
|
|
SFTPB
|
surfactant protein B
|
3.50964
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.45962
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.42947
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
3.17682
|
|
NMU
|
neuromedin U
|
3.11209
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.79435
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.49276
|
|
SH3D19
|
SH3 domain containing 19
|
2.41704
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.30579
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.28083
|
|
GHR
|
growth hormone receptor
|
2.27272
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.24483
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
2.2407
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.19941
|
|
EPHA3
|
EPH receptor A3
|
2.14456
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.11213
|
|
PMM2
|
phosphomannomutase 2
|
2.03718
|
|
MMP1
|
matrix metallopeptidase 1
|
2.0037
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-8.47034
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.10677
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.14617
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-4.85206
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-4.31529
|
|
NVL
|
nuclear VCP-like
|
-4.23493
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.20232
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.05688
|
|
ZNF586
|
zinc finger protein 586
|
-3.6497
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.52519
|
|
HMG20B
|
high mobility group 20B
|
-3.1597
|
|
LYPLA1
|
lysophospholipase I
|
-2.62306
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.61142
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.52147
|
|
GSR
|
glutathione reductase
|
-2.16162
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.05026
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.03736
|
