CRCGN014_HEPG2_24H:L22 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_24H:L22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
7.12911
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.80283
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.59107
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.37664
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.02185
|
|
GPATCH8
|
G patch domain containing 8
|
3.0095
|
|
MYLK
|
myosin light chain kinase
|
2.91914
|
|
UBQLN2
|
ubiquilin 2
|
2.82249
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.77273
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.73633
|
|
CYCS
|
cytochrome c, somatic
|
2.6416
|
|
CHN1
|
chimerin 1
|
2.38799
|
|
JADE1
|
jade family PHD finger 1
|
2.30755
|
|
MAP7
|
microtubule-associated protein 7
|
2.2705
|
|
TSPAN6
|
tetraspanin 6
|
2.22441
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.14896
|
|
MCUB
|
mitochondrial calcium uniporter dominant negative subunit beta
|
2.06383
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
TRIB3
|
tribbles pseudokinase 3
|
-7.48731
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.96784
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.69605
|
|
GNAS
|
GNAS complex locus
|
-4.49889
|
|
CD320
|
CD320 molecule
|
-4.17815
|
|
DNM1L
|
dynamin 1-like
|
-3.83346
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.67997
|
|
ZNF586
|
zinc finger protein 586
|
-3.64514
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.501
|
|
CCNB2
|
cyclin B2
|
-3.43786
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.03534
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.00408
|
|
CDC20
|
cell division cycle 20
|
-2.84841
|
|
STX4
|
syntaxin 4
|
-2.70237
|
|
BMP4
|
bone morphogenetic protein 4
|
-2.59478
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.43658
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.387
|
|
NT5DC3
|
5'-nucleotidase domain containing 3
|
-2.19828
|
