CRCGN014_HEPG2_24H:L24 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_24H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
4.24297
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.99883
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.69916
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.66025
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.49872
|
|
STIMATE
|
STIM activating enhancer
|
3.34009
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
3.15293
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.08654
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.04057
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.92467
|
|
KIF20A
|
kinesin family member 20A
|
2.64899
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.54996
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.51759
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.49156
|
|
SEC24B
|
SEC24 family member B
|
2.23046
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.2201
|
|
JADE2
|
jade family PHD finger 2
|
2.18279
|
|
S100A4
|
S100 calcium binding protein A4
|
2.15547
|
|
STAM
|
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
|
2.08113
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.04788
|
|
CCNF
|
cyclin F
|
2.04407
|
|
PUDP
|
pseudouridine 5'-phosphatase
|
2.02025
|
|
PCID2
|
PCI domain containing 2
|
2.00795
|
|
CBR3
|
carbonyl reductase 3
|
2.00673
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FASTKD5
|
FAST kinase domains 5
|
-5.61932
|
|
GNAS
|
GNAS complex locus
|
-5.49198
|
|
ZNF586
|
zinc finger protein 586
|
-4.44055
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.92923
|
|
RPN1
|
ribophorin I
|
-3.76188
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.72094
|
|
GOLT1B
|
golgi transport 1B
|
-3.71812
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.61267
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.50494
|
|
TLR4
|
toll-like receptor 4
|
-3.343
|
|
RNF167
|
ring finger protein 167
|
-3.27132
|
|
LYPLA1
|
lysophospholipase I
|
-2.93168
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.91314
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.53447
|
|
EGF
|
epidermal growth factor
|
-2.4498
|
|
BEAN1
|
brain expressed, associated with NEDD4, 1
|
-2.41261
|
|
CDC25B
|
cell division cycle 25B
|
-2.40881
|
|
POU3F2
|
POU class 3 homeobox 2
|
-2.39791
|
|
CCDC102B
|
coiled-coil domain containing 102B
|
-2.33283
|
|
DAZ2
|
deleted in azoospermia 2
|
-2.22322
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.21753
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.16854
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.07779
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.03223
|
