CRCGN014_HEPG2_24H:M04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description furan 38.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN014_HEPG2_24H:M04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHMP6 charged multivesicular body protein 6 6.59431
CCL2 chemokine (C-C motif) ligand 2 3.39277
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.25045
DIPK1A divergent protein kinase domain 1A 3.06328
ABHD6 abhydrolase domain containing 6 3.02425
GPER1 G protein-coupled estrogen receptor 1 2.74779
LCN2 lipocalin 2 2.7201
MAP7 microtubule-associated protein 7 2.66722
KIF20A kinesin family member 20A 2.60982
CYCS cytochrome c, somatic 2.49486
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.37615
CCNF cyclin F 2.37541
HLA-DRA major histocompatibility complex, class II, DR alpha 2.13992
WASF3 WAS protein family, member 3 2.12039
PEX11A peroxisomal biogenesis factor 11 alpha 2.04357
DYNLT3 dynein, light chain, Tctex-type 3 2.00169

decreased expression

Symbol Name Standardized Value
TLCD3A TLC domain containing 3A -4.82258
CCNB2 cyclin B2 -4.7055
HMG20B high mobility group 20B -4.67489
MRPS2 mitochondrial ribosomal protein S2 -3.81646
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.75121
NRIP1 nuclear receptor interacting protein 1 -3.5825
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.53499
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.39228
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.33312
OXA1L oxidase (cytochrome c) assembly 1-like -3.31045
UGDH UDP-glucose 6-dehydrogenase -3.18198
LDHD lactate dehydrogenase D -2.98192
GTPBP8 GTP-binding protein 8 (putative) -2.96592
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.81195
ZNF586 zinc finger protein 586 -2.80253
WASHC4 WASH complex subunit 4 -2.671
SNX11 sorting nexin 11 -2.34375
RNF167 ring finger protein 167 -2.15117
EGF epidermal growth factor -2.0556