| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | barium chloride dihydrate 40.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN014_HEPG2_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 7.4934 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.12546 |
| UBQLN2 | ubiquilin 2 | 5.70242 |
| ADRB2 | adrenoceptor beta 2, surface | 4.84248 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.80618 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.3926 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.33009 |
| FZD7 | frizzled class receptor 7 | 4.31363 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.25495 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.20614 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.05626 |
| EVL | Enah/Vasp-like | 3.95545 |
| STIMATE | STIM activating enhancer | 3.60153 |
| RPL39L | ribosomal protein L39-like | 3.24628 |
| JADE2 | jade family PHD finger 2 | 3.21209 |
| SFTPB | surfactant protein B | 2.96626 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 2.9333 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.8363 |
| CBR3 | carbonyl reductase 3 | 2.78149 |
| SIRT3 | sirtuin 3 | 2.67784 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.67436 |
| NOTCH1 | notch 1 | 2.63714 |
| CHMP6 | charged multivesicular body protein 6 | 2.61934 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.49096 |
| E2F2 | E2F transcription factor 2 | 2.42098 |
| LCN2 | lipocalin 2 | 2.4161 |
| EPHB2 | EPH receptor B2 | 2.31452 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.22816 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.16398 |
| PLSCR1 | phospholipid scramblase 1 | 2.11921 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.1053 |
| C8A | complement component 8, alpha polypeptide | 2.10094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.94227 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.54237 |
| LDHD | lactate dehydrogenase D | -4.058 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.73445 |
| SPAG4 | sperm associated antigen 4 | -3.68044 |
| CCDC86 | coiled-coil domain containing 86 | -3.57192 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.52942 |
| CCNB2 | cyclin B2 | -3.45699 |
| LAP3 | leucine aminopeptidase 3 | -3.32795 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.28589 |
| PPOX | protoporphyrinogen oxidase | -3.26493 |
| DSG2 | desmoglein 2 | -3.20535 |
| COG7 | component of oligomeric golgi complex 7 | -3.11423 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -3.01675 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.97156 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.93217 |
| CDC25B | cell division cycle 25B | -2.92264 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.86895 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.67877 |
| NUP85 | nucleoporin 85kDa | -2.40428 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.39715 |
| RPS5 | ribosomal protein S5 | -2.35464 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.26099 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.25406 |
| CD58 | CD58 molecule | -2.16902 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -2.12128 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.10023 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.0829 |
| YME1L1 | YME1-like 1 ATPase | -2.04995 |
| ZNF692 | zinc finger protein 692 | -2.02877 |
