CRCGN014_HEPG2_24H:M06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 39.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN014_HEPG2_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 9.40957
BLMH bleomycin hydrolase 4.87523
UBQLN2 ubiquilin 2 4.45267
PPARG peroxisome proliferator-activated receptor gamma 4.37029
SATB1 SATB homeobox 1 3.38976
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.25498
EPN2 epsin 2 3.22124
TREM1 triggering receptor expressed on myeloid cells 1 2.99972
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.91125
KIF20A kinesin family member 20A 2.78026
CCNF cyclin F 2.44979
NMU neuromedin U 2.35637
SOCS2 suppressor of cytokine signaling 2 2.25925
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.13826
CHN1 chimerin 1 2.12883
HLA-DRA major histocompatibility complex, class II, DR alpha 2.10484
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.03556

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -4.62086
GOLT1B golgi transport 1B -4.47338
DNM1L dynamin 1-like -4.39866
ZNF586 zinc finger protein 586 -3.84973
TRIB3 tribbles pseudokinase 3 -3.83047
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.82478
CCNB2 cyclin B2 -2.70209
RGS2 regulator of G-protein signaling 2 -2.3369
PTPRK protein tyrosine phosphatase, receptor type, K -2.31782
ELOVL1 ELOVL fatty acid elongase 1 -2.31752
VDAC1 voltage-dependent anion channel 1 -2.25408
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.24399
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -2.24188
RGS16 regulator of G-protein signaling 16 -2.23227
ICAM3 intercellular adhesion molecule 3 -2.13014
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.10818
RPS5 ribosomal protein S5 -2.08281
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.02228