CRCGN014_HEPG2_24H:M06 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
9.40957
|
|
BLMH
|
bleomycin hydrolase
|
4.87523
|
|
UBQLN2
|
ubiquilin 2
|
4.45267
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.37029
|
|
SATB1
|
SATB homeobox 1
|
3.38976
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
3.25498
|
|
EPN2
|
epsin 2
|
3.22124
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.99972
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.91125
|
|
KIF20A
|
kinesin family member 20A
|
2.78026
|
|
CCNF
|
cyclin F
|
2.44979
|
|
NMU
|
neuromedin U
|
2.35637
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.25925
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.13826
|
|
CHN1
|
chimerin 1
|
2.12883
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.10484
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.03556
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-4.62086
|
|
GOLT1B
|
golgi transport 1B
|
-4.47338
|
|
DNM1L
|
dynamin 1-like
|
-4.39866
|
|
ZNF586
|
zinc finger protein 586
|
-3.84973
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.83047
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.82478
|
|
CCNB2
|
cyclin B2
|
-2.70209
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.3369
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.31782
|
|
ELOVL1
|
ELOVL fatty acid elongase 1
|
-2.31752
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.25408
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
-2.24399
|
|
TIE1
|
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
|
-2.24188
|
|
RGS16
|
regulator of G-protein signaling 16
|
-2.23227
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.13014
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.10818
|
|
RPS5
|
ribosomal protein S5
|
-2.08281
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.02228
|