CRCGN014_HEPG2_24H:M08 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.91593
|
|
SFTPB
|
surfactant protein B
|
3.76306
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.7477
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.4398
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.30566
|
|
E2F2
|
E2F transcription factor 2
|
3.19366
|
|
STIMATE
|
STIM activating enhancer
|
2.92864
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.83363
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.51969
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.44492
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.42379
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.3377
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.23116
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.21504
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.16308
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.14976
|
|
CHCHD7
|
coiled-coil-helix-coiled-coil-helix domain containing 7
|
2.13704
|
|
CYCS
|
cytochrome c, somatic
|
2.01186
|
|
SATB1
|
SATB homeobox 1
|
2.0064
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.41327
|
|
ZNF586
|
zinc finger protein 586
|
-4.92197
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.72808
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.13204
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.84866
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.72609
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.70056
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.56448
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.44638
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.31616
|
|
SCAND1
|
SCAN domain containing 1
|
-3.19144
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.11874
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-3.11634
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.09865
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.87889
|
|
CDC20
|
cell division cycle 20
|
-2.84261
|
|
RHEB
|
Ras homolog enriched in brain
|
-2.56858
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.37898
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.29113
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.28169
|
|
PLK1
|
polo-like kinase 1
|
-2.24681
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.08855
|
