| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-(chloromethyl)pyridine.hcl 39.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN014_HEPG2_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPHB2 | EPH receptor B2 | 7.0967 |
| UBQLN2 | ubiquilin 2 | 6.97705 |
| NOTCH1 | notch 1 | 6.86701 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.49288 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.9892 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.85686 |
| CCNF | cyclin F | 4.67877 |
| E2F2 | E2F transcription factor 2 | 4.58392 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.8614 |
| KLHL21 | kelch-like family member 21 | 3.54398 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.44443 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.40508 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.39946 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.83994 |
| ECD | ecdysoneless homolog (Drosophila) | 2.63491 |
| PRKCH | protein kinase C, eta | 2.59501 |
| CCNE1 | cyclin E1 | 2.49277 |
| CHN1 | chimerin 1 | 2.32335 |
| ADRB2 | adrenoceptor beta 2, surface | 2.21974 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.21062 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 | 2.18899 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.1878 |
| SIPA1 | signal-induced proliferation-associated 1 | 2.10822 |
| LY6G6F-LY6G6D | LY6G6F-LY6G6D readthrough | 2.09965 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | 2.03712 |
| KIFBP | kinesin family binding protein | 2.02659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| YME1L1 | YME1-like 1 ATPase | -4.78219 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.66559 |
| ADI1 | acireductone dioxygenase 1 | -4.01804 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -3.67285 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.60334 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.58354 |
| LDHD | lactate dehydrogenase D | -3.14174 |
| CCNB2 | cyclin B2 | -3.02142 |
| COG2 | component of oligomeric golgi complex 2 | -2.9286 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -2.90654 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.70613 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.62641 |
| DNM1L | dynamin 1-like | -2.51672 |
| TMEM45A | transmembrane protein 45A | -2.49203 |
| CCDC86 | coiled-coil domain containing 86 | -2.39425 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.32071 |
| TUBB6 | tubulin, beta 6 class V | -2.31743 |
| RBM15B | RNA binding motif protein 15B | -2.30754 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -2.28253 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.24025 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.18119 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -2.15568 |
| CDC20 | cell division cycle 20 | -2.15418 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | -2.12859 |
| PRR11 | proline rich 11 | -2.09065 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -2.01148 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.00246 |
| TFF2 | trefoil factor 2 | -2.00188 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.0014 |
