CRCGN014_HEPG2_24H:M10 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
6.11742
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.31075
|
|
PRR15L
|
proline rich 15-like
|
3.96503
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
3.5376
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.39428
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.28423
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.19988
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.12363
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.09575
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.07435
|
|
CBR3
|
carbonyl reductase 3
|
3.02502
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.52449
|
|
KIF20A
|
kinesin family member 20A
|
2.47966
|
|
BAX
|
BCL2-associated X protein
|
2.45771
|
|
KLHL9
|
kelch-like family member 9
|
2.30735
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.30157
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.29691
|
|
FZD7
|
frizzled class receptor 7
|
2.1296
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-6.6623
|
|
LDHD
|
lactate dehydrogenase D
|
-6.58887
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-6.53645
|
|
TLR4
|
toll-like receptor 4
|
-5.39941
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.6461
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.90135
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.45516
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.40436
|
|
SNX11
|
sorting nexin 11
|
-3.37094
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.35811
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.29722
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.26209
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.18793
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.9969
|
|
CDC20
|
cell division cycle 20
|
-2.99606
|
|
CCNB1
|
cyclin B1
|
-2.73832
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.73579
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.42085
|
|
KLF4
|
Kruppel-like factor 4 (gut)
|
-2.39047
|
|
GDF15
|
growth differentiation factor 15
|
-2.35065
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.29885
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.22174
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.15982
|
|
TES
|
testin LIM domain protein
|
-2.12337
|
|
CCR9
|
chemokine (C-C motif) receptor 9
|
-2.11158
|
|
SOX3
|
SRY (sex determining region Y)-box 3
|
-2.04142
|
