CRCGN014_HEPG2_24H:M11 Gene Set
Genes
42 genes differentially expressed following the CRCGN014_HEPG2_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.38529
|
|
GPATCH8
|
G patch domain containing 8
|
4.02561
|
|
NOTCH1
|
notch 1
|
3.66565
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
3.61078
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.54626
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.37757
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.33576
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
3.27145
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.08798
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.46064
|
|
CCNF
|
cyclin F
|
2.312
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.24748
|
|
CSK
|
c-src tyrosine kinase
|
2.233
|
|
CX3CR1
|
chemokine (C-X3-C motif) receptor 1
|
2.22767
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.11242
|
|
GATA3
|
GATA binding protein 3
|
2.01907
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.42045
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.19898
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.12999
|
|
ZNF586
|
zinc finger protein 586
|
-4.06845
|
|
NUP85
|
nucleoporin 85kDa
|
-3.87595
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.58545
|
|
LDHD
|
lactate dehydrogenase D
|
-3.53532
|
|
VAT1
|
vesicle amine transport 1
|
-3.53448
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.38574
|
|
CCNB2
|
cyclin B2
|
-3.1437
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.99362
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.9177
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.89934
|
|
TMEM94
|
transmembrane protein 94
|
-2.86215
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.67098
|
|
TLR4
|
toll-like receptor 4
|
-2.36502
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.34519
|
|
SLAMF7
|
SLAM family member 7
|
-2.31756
|
|
HMG20B
|
high mobility group 20B
|
-2.20099
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.1531
|
|
GOLT1B
|
golgi transport 1B
|
-2.12282
|
|
OR10C1
|
olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
|
-2.08276
|
|
CASKIN2
|
CASK interacting protein 2
|
-2.06659
|
|
TSSK2
|
testis-specific serine kinase 2
|
-2.01828
|
|
FRS3
|
fibroblast growth factor receptor substrate 3
|
-2.00802
|
|
SLC9A2
|
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
|
-2.00615
|
