CRCGN014_HEPG2_24H:M12 Gene Set
Genes
34 genes differentially expressed following the CRCGN014_HEPG2_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.69243
|
|
MYLK
|
myosin light chain kinase
|
4.70609
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.52106
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.4807
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.31325
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.3131
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.94595
|
|
NOTCH1
|
notch 1
|
3.8671
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.75566
|
|
PCDHB11
|
protocadherin beta 11
|
3.51528
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.26713
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.86111
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.70854
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.47857
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.25088
|
|
NMU
|
neuromedin U
|
2.21814
|
|
SFTPB
|
surfactant protein B
|
2.19288
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-5.71237
|
|
CTSD
|
cathepsin D
|
-4.50568
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.45925
|
|
DNM1L
|
dynamin 1-like
|
-4.42937
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.25726
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-4.12653
|
|
CD320
|
CD320 molecule
|
-4.09701
|
|
NUP85
|
nucleoporin 85kDa
|
-3.99764
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.68393
|
|
SNX11
|
sorting nexin 11
|
-3.39914
|
|
TLR4
|
toll-like receptor 4
|
-2.849
|
|
VAT1
|
vesicle amine transport 1
|
-2.79006
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.24709
|
|
DHRS7B
|
dehydrogenase/reductase (SDR family) member 7B
|
-2.23402
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.03011
|
|
CCNB2
|
cyclin B2
|
-2.01157
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.00913
|
