CRCGN014_HEPG2_24H:M16 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
5.10114
|
|
UBQLN2
|
ubiquilin 2
|
4.27627
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.10423
|
|
STK10
|
serine/threonine kinase 10
|
3.75563
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.04246
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
3.02543
|
|
CDC45
|
cell division cycle 45
|
3.01625
|
|
GPATCH8
|
G patch domain containing 8
|
2.98311
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.97064
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.82198
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.77941
|
|
PRKCH
|
protein kinase C, eta
|
2.58873
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.51513
|
|
UBE2L6
|
ubiquitin-conjugating enzyme E2L 6
|
2.46651
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
2.43918
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.34897
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
2.29021
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.23244
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.12923
|
|
CYCS
|
cytochrome c, somatic
|
2.12575
|
|
FUT1
|
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
|
2.09133
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.08604
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.07059
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.05224
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
2.01
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-5.89479
|
|
ZNF586
|
zinc finger protein 586
|
-4.23584
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-3.21528
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.18689
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.07552
|
|
GOLT1B
|
golgi transport 1B
|
-3.07158
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.92073
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.86287
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.73165
|
|
TLR4
|
toll-like receptor 4
|
-2.34566
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.28952
|
|
CDC25B
|
cell division cycle 25B
|
-2.26313
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
-2.25285
|
|
SPAG4
|
sperm associated antigen 4
|
-2.148
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.13346
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.08953
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
-2.06457
|
|
ZW10
|
zw10 kinetochore protein
|
-2.02614
|
