CRCGN014_HEPG2_24H:M17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,4'-ddt 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

415 genes differentially expressed following the CRCGN014_HEPG2_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNPY3 canopy FGF signaling regulator 3 7.44283
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 6.36382
STX1A syntaxin 1A (brain) 6.05921
TRIB3 tribbles pseudokinase 3 5.88494
INPP1 inositol polyphosphate-1-phosphatase 5.78804
GRB10 growth factor receptor-bound protein 10 5.49506
MICALL1 MICAL-like 1 5.33095
FOSL1 FOS-like antigen 1 5.32993
TIMP2 TIMP metallopeptidase inhibitor 2 5.3196
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.22539
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.19072
KIFBP kinesin family binding protein 5.12873
KLHL21 kelch-like family member 21 5.09174
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.69943
IER3 immediate early response 3 4.6372
MVP major vault protein 4.57879
SQOR sulfide quinone oxidoreductase 4.55343
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 4.14058
CAB39 calcium binding protein 39 4.13962
IGFBP3 insulin-like growth factor binding protein 3 4.13195
PRAF2 PRA1 domain family, member 2 4.0745
GFPT1 glutamine--fructose-6-phosphate transaminase 1 4.06936
IL4R interleukin 4 receptor 3.99186
LCN2 lipocalin 2 3.98668
ANO1 anoctamin 1, calcium activated chloride channel 3.97745
MYC v-myc avian myelocytomatosis viral oncogene homolog 3.946
TOMM34 translocase of outer mitochondrial membrane 34 3.78336
ZFP36 ZFP36 ring finger protein 3.77592
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.77259
DDIT4 DNA-damage-inducible transcript 4 3.76455
SLC35F2 solute carrier family 35, member F2 3.76449
NANOS3 nanos homolog 3 (Drosophila) 3.63505
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.62662
BZW2 basic leucine zipper and W2 domains 2 3.60093
NPDC1 neural proliferation, differentiation and control, 1 3.57699
ACOT9 acyl-CoA thioesterase 9 3.55627
VAT1 vesicle amine transport 1 3.41935
SMAD3 SMAD family member 3 3.40358
YARS1 tyrosyl-tRNA synthetase 1 3.39606
SARS1 seryl-tRNA synthetase 1 3.36312
TRIB1 tribbles pseudokinase 1 3.31411
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.28564
PDGFA platelet-derived growth factor alpha polypeptide 3.23402
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.20326
EGR1 early growth response 1 3.1934
CXCR4 chemokine (C-X-C motif) receptor 4 3.19069
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 3.17196
NOTCH1 notch 1 3.17192
TXNRD1 thioredoxin reductase 1 3.16948
CASC3 cancer susceptibility candidate 3 3.14317
SOX4 SRY (sex determining region Y)-box 4 3.13538
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.13223
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 3.12254
FOS FBJ murine osteosarcoma viral oncogene homolog 3.09089
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.06463
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.04948
DSG2 desmoglein 2 3.04912
ATF6 activating transcription factor 6 3.03101
CXCL2 chemokine (C-X-C motif) ligand 2 3.02058
FPGS folylpolyglutamate synthase 2.9744
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.95649
SQSTM1 sequestosome 1 2.94877
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.90922
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.86577
BIRC2 baculoviral IAP repeat containing 2 2.85274
TERF2IP telomeric repeat binding factor 2, interacting protein 2.84473
CHN1 chimerin 1 2.84047
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.83792
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.835
GARS1 glycyl-tRNA synthetase 1 2.83499
SFXN3 sideroflexin 3 2.83423
GTPBP2 GTP binding protein 2 2.8244
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.80187
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.76763
TES testin LIM domain protein 2.75323
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.69707
PPARG peroxisome proliferator-activated receptor gamma 2.69188
AARS1 alanyl-tRNA synthetase 1 2.69065
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.68078
NPC1 Niemann-Pick disease, type C1 2.66385
FLCN folliculin 2.6565
DNM1L dynamin 1-like 2.65136
RALB v-ral simian leukemia viral oncogene homolog B 2.63263
CSNK1E casein kinase 1, epsilon 2.63181
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.62212
MAPK13 mitogen-activated protein kinase 13 2.61272
F2R coagulation factor II (thrombin) receptor 2.58668
TICAM1 toll-like receptor adaptor molecule 1 2.57909
LRP10 low density lipoprotein receptor-related protein 10 2.55404
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 2.5312
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.50747
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.49799
PRKCQ protein kinase C, theta 2.49266
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.47872
CYCS cytochrome c, somatic 2.45885
ARID5B AT rich interactive domain 5B (MRF1-like) 2.41827
CARS1 cysteinyl-tRNA synthetase 1 2.41225
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.39927
PRR15L proline rich 15-like 2.3865
NUP58 nucleoporin 58 2.37996
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.36961
MEAF6 MYST/Esa1-associated factor 6 2.36502
PPARD peroxisome proliferator-activated receptor delta 2.35797
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.33991
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.33775
TRIM13 tripartite motif containing 13 2.33711
YIPF3 Yip1 domain family, member 3 2.33564
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.32745
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.32575
MAP7D1 MAP7 domain containing 1 2.32306
CAMTA2 calmodulin binding transcription activator 2 2.32019
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.31393
DENND4C DENN/MADD domain containing 4C 2.30807
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.30215
CDH5 cadherin 5, type 2 (vascular endothelium) 2.30047
ALAS1 5'-aminolevulinate synthase 1 2.29905
MCOLN3 mucolipin 3 2.29456
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.29342
KDM5A lysine (K)-specific demethylase 5A 2.28942
MBNL2 muscleblind-like splicing regulator 2 2.28894
FHOD1 formin homology 2 domain containing 1 2.28711
BICRAL BICRA like chromatin remodeling complex associated protein 2.28068
STN1 STN1 subunit of CST complex 2.2763
MTMR6 myotubularin related protein 6 2.27384
KRT86 keratin 86, type II 2.25706
IQGAP1 IQ motif containing GTPase activating protein 1 2.25373
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.24691
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.23673
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.23635
ANKRD11 ankyrin repeat domain 11 2.22754
MTERF3 mitochondrial transcription termination factor 3 2.22541
IFRD1 interferon-related developmental regulator 1 2.22358
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.22002
EIF6 eukaryotic translation initiation factor 6 2.21609
XPOT exportin, tRNA 2.21369
GIPC1 GIPC PDZ domain containing family, member 1 2.21199
SH2B3 SH2B adaptor protein 3 2.19578
ASCC1 activating signal cointegrator 1 complex subunit 1 2.19432
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.19238
DUSP6 dual specificity phosphatase 6 2.19222
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.18946
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.18622
MYO5A myosin VA (heavy chain 12, myoxin) 2.1862
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 2.18423
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.17173
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.16609
MRPL37 mitochondrial ribosomal protein L37 2.16512
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.16036
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.142
TRIM8 tripartite motif containing 8 2.13208
TREM1 triggering receptor expressed on myeloid cells 1 2.13189
LORICRIN loricrin cornified envelope precursor protein 2.12664
MEA1 male-enhanced antigen 1 2.12424
THBD thrombomodulin 2.12163
CCDC85B coiled-coil domain containing 85B 2.11963
BECN1 beclin 1, autophagy related 2.11679
LOC128125814 uncharacterized LOC128125814 2.11529
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.11293
RGS10 regulator of G-protein signaling 10 2.10833
ZBTB35 zinc finger and BTB domain containing 35 2.10598
CLTB clathrin, light chain B 2.10035
FBXO7 F-box protein 7 2.09837
ACTN4 actinin, alpha 4 2.09645
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.09583
TPM4 tropomyosin 4 2.09342
RBKS ribokinase 2.09127
GSK3B glycogen synthase kinase 3 beta 2.08987
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.08712
SUN2 Sad1 and UNC84 domain containing 2 2.08248
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.07371
MACF1 microtubule-actin crosslinking factor 1 2.06656
ITCH itchy E3 ubiquitin protein ligase 2.0611
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.05956
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.05798
MMRN2 multimerin 2 2.05483
S100A11 S100 calcium binding protein A11 2.05395
BYSL bystin-like 2.0494
RNF103-CHMP3 RNF103-CHMP3 readthrough 2.04883
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.04415
KLF6 Kruppel-like factor 6 2.04085
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.03667
TBPL1 TBP-like 1 2.03339
TRAM2 translocation associated membrane protein 2 2.02843
IER2 immediate early response 2 2.0245
CD9 CD9 molecule 2.02371
SUMF2 sulfatase modifying factor 2 2.02266
JOSD1 Josephin domain containing 1 2.02257
FZD1 frizzled class receptor 1 2.01275
RNF24 ring finger protein 24 2.0082
ABHD6 abhydrolase domain containing 6 2.00793
VEZT vezatin, adherens junctions transmembrane protein 2.00749
MNT MAX network transcriptional repressor 2.00741
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.00636
EHD4 EH-domain containing 4 2.00344

decreased expression

Symbol Name Standardized Value
B4GAT1 beta-1,4-glucuronyltransferase 1 -7.84887
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -7.00836
MELK maternal embryonic leucine zipper kinase -6.88507
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.51239
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.0121
RPS4Y1 ribosomal protein S4, Y-linked 1 -5.68711
PSRC1 proline/serine-rich coiled-coil 1 -5.6387
CCNB1 cyclin B1 -5.5907
DERA deoxyribose-phosphate aldolase (putative) -5.5607
TCTN1 tectonic family member 1 -5.3659
CDK1 cyclin-dependent kinase 1 -5.31773
CCNA2 cyclin A2 -5.28611
TOP2A topoisomerase (DNA) II alpha 170kDa -5.17963
UBE2C ubiquitin-conjugating enzyme E2C -5.16686
ISOC1 isochorismatase domain containing 1 -5.12683
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -4.94197
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.88161
ADI1 acireductone dioxygenase 1 -4.75887
BIRC5 baculoviral IAP repeat containing 5 -4.66069
PLK1 polo-like kinase 1 -4.54061
PCNA proliferating cell nuclear antigen -4.52418
LBR lamin B receptor -4.43708
CD320 CD320 molecule -4.40437
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.324
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.3177
BLCAP bladder cancer associated protein -4.26977
AURKB aurora kinase B -4.25602
ECH1 enoyl CoA hydratase 1, peroxisomal -4.16597
CDC20 cell division cycle 20 -4.16099
ANKRD10 ankyrin repeat domain 10 -4.09183
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.03863
PGAM4 phosphoglycerate mutase family member 4 -4.005
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.97093
TSPAN4 tetraspanin 4 -3.97059
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.87875
NT5DC2 5'-nucleotidase domain containing 2 -3.86389
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.84868
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.81287
TMEM109 transmembrane protein 109 -3.79038
LDHD lactate dehydrogenase D -3.75622
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.72158
PARP1 poly (ADP-ribose) polymerase 1 -3.71946
ASF1B anti-silencing function 1B histone chaperone -3.68959
CRELD2 cysteine-rich with EGF-like domains 2 -3.64922
ICAM3 intercellular adhesion molecule 3 -3.61988
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.56897
STMN1 stathmin 1 -3.54659
MCM10 minichromosome maintenance complex component 10 -3.5284
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.45624
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.44272
PGM1 phosphoglucomutase 1 -3.42178
TK1 thymidine kinase 1, soluble -3.38883
HAT1 histone acetyltransferase 1 -3.35483
TEDC2 tubulin epsilon and delta complex 2 -3.33953
NRIP1 nuclear receptor interacting protein 1 -3.25735
ALDOC aldolase C, fructose-bisphosphate -3.24084
CHEK2 checkpoint kinase 2 -3.2336
KIF11 kinesin family member 11 -3.23357
ACAA1 acetyl-CoA acyltransferase 1 -3.21645
TLR4 toll-like receptor 4 -3.19771
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.17466
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.15602
NUP85 nucleoporin 85kDa -3.0875
CDC25B cell division cycle 25B -3.06545
HADH hydroxyacyl-CoA dehydrogenase -3.06132
DCK deoxycytidine kinase -3.01317
RPA3 replication protein A3, 14kDa -2.991
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.97696
MLEC malectin -2.95797
FEN1 flap structure-specific endonuclease 1 -2.9446
KIF4A kinesin family member 4A -2.91743
FANCI Fanconi anemia, complementation group I -2.91197
HMGA2 high mobility group AT-hook 2 -2.90657
COG4 component of oligomeric golgi complex 4 -2.90034
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.8782
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.86664
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.84443
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.82782
ZNF586 zinc finger protein 586 -2.81122
TFDP1 transcription factor Dp-1 -2.8014
SOAT2 sterol O-acyltransferase 2 -2.78364
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.77656
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.7601
EXO1 exonuclease 1 -2.75024
ELP4 elongator acetyltransferase complex subunit 4 -2.7487
TRIP13 thyroid hormone receptor interactor 13 -2.74381
CDC25A cell division cycle 25A -2.73976
KIF15 kinesin family member 15 -2.73201
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.71142
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.70356
NCAPH non-SMC condensin I complex, subunit H -2.6996
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.69315
NISCH nischarin -2.67952
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.67821
PROS1 protein S (alpha) -2.6566
GLRX5 glutaredoxin 5 -2.6395
TMEM97 transmembrane protein 97 -2.61647
CDK2 cyclin-dependent kinase 2 -2.6114
POLK polymerase (DNA directed) kappa -2.5963
NFIL3 nuclear factor, interleukin 3 regulated -2.59088
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.57258
DNAAF2 dynein, axonemal, assembly factor 2 -2.56902
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.56523
FZD7 frizzled class receptor 7 -2.55614
PCCB propionyl CoA carboxylase, beta polypeptide -2.52108
PGRMC1 progesterone receptor membrane component 1 -2.51768
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.5167
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.51
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.50846
CDC6 cell division cycle 6 -2.49857
PRCP prolylcarboxypeptidase (angiotensinase C) -2.49259
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.48405
THAP11 THAP domain containing 11 -2.48337
FGFR4 fibroblast growth factor receptor 4 -2.48263
TBC1D10C TBC1 domain family, member 10C -2.44827
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.43767
SPAG5 sperm associated antigen 5 -2.42017
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.41511
DSCC1 DNA replication and sister chromatid cohesion 1 -2.41217
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.40134
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.39592
PARPBP PARP1 binding protein -2.39412
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.38947
ERCC6L excision repair cross-complementation group 6-like -2.38743
BLM Bloom syndrome, RecQ helicase-like -2.37981
RNF123 ring finger protein 123 -2.37405
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.36443
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.35757
SPDEF SAM pointed domain containing ETS transcription factor -2.34947
NRTN neurturin -2.34423
RBM15B RNA binding motif protein 15B -2.34402
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.34387
DHFR dihydrofolate reductase -2.34052
NNT nicotinamide nucleotide transhydrogenase -2.33694
STAT1 signal transducer and activator of transcription 1, 91kDa -2.33492
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.33391
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.30181
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.29958
KIF22 kinesin family member 22 -2.29954
UNC119 unc-119 homolog (C. elegans) -2.29584
PRPF4 pre-mRNA processing factor 4 -2.2917
LMNB1 lamin B1 -2.28495
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.27154
RMI1 RecQ mediated genome instability 1 -2.26143
AMT aminomethyltransferase -2.25832
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.25676
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.25546
KIFC1 kinesin family member C1 -2.23799
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.23243
INTS5 integrator complex subunit 5 -2.23063
RAD54L RAD54-like (S. cerevisiae) -2.22014
PDGFRL platelet-derived growth factor receptor-like -2.21755
RPIA ribose 5-phosphate isomerase A -2.21496
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.21434
MYCBP MYC binding protein -2.20999
CENPM centromere protein M -2.20974
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.20771
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.20575
OIP5 Opa interacting protein 5 -2.19529
TMPRSS6 transmembrane protease, serine 6 -2.19447
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.19152
MCM5 minichromosome maintenance complex component 5 -2.18764
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.18714
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.18397
MRPL16 mitochondrial ribosomal protein L16 -2.18295
ZWINT ZW10 interacting kinetochore protein -2.17935
GTF2A2 general transcription factor IIA, 2, 12kDa -2.17176
CDC45 cell division cycle 45 -2.17088
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.16978
NUP107 nucleoporin 107kDa -2.16755
MSH6 mutS homolog 6 -2.1601
CDCA8 cell division cycle associated 8 -2.16009
TTC38 tetratricopeptide repeat domain 38 -2.15997
QTRT1 queuine tRNA-ribosyltransferase 1 -2.1554
BLMH bleomycin hydrolase -2.15468
NLRP2B NLR family pyrin domain containing 2B -2.14948
KLHDC2 kelch domain containing 2 -2.14675
HSPB1 heat shock 27kDa protein 1 -2.14662
OXA1L oxidase (cytochrome c) assembly 1-like -2.13344
STIMATE STIM activating enhancer -2.13166
HMGN3 high mobility group nucleosomal binding domain 3 -2.12975
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.12888
RPS5 ribosomal protein S5 -2.12509
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.12297
MVD mevalonate (diphospho) decarboxylase -2.12061
INCENP inner centromere protein antigens 135/155kDa -2.11281
CEP76 centrosomal protein 76kDa -2.11154
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.11002
GCH1 GTP cyclohydrolase 1 -2.10995
CAAP1 caspase activity and apoptosis inhibitor 1 -2.10388
SPDL1 spindle apparatus coiled-coil protein 1 -2.09895
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.09598
PSKH1 protein serine kinase H1 -2.07887
TMPO thymopoietin -2.07607
FANCG Fanconi anemia, complementation group G -2.07165
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.06422
DDB2 damage-specific DNA binding protein 2, 48kDa -2.06416
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.06102
GMNN geminin, DNA replication inhibitor -2.05788
CEP55 centrosomal protein 55kDa -2.05418
HMGB2 high mobility group box 2 -2.0489
TRAIP TRAF interacting protein -2.04292
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.04282
CLCN2 chloride channel, voltage-sensitive 2 -2.03842
PXMP2 peroxisomal membrane protein 2, 22kDa -2.03518
CLASRP CLK4-associating serine/arginine rich protein -2.03516
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.0341
ECT2 epithelial cell transforming 2 -2.03129
AUH AU RNA binding protein/enoyl-CoA hydratase -2.03108
RFC3 replication factor C (activator 1) 3, 38kDa -2.02718
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.02625
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 -2.02095
NCAPG2 non-SMC condensin II complex, subunit G2 -2.02062
CDCA3 cell division cycle associated 3 -2.01518
LRRC61 leucine rich repeat containing 61 -2.01316
CHMP6 charged multivesicular body protein 6 -2.01068
ANKFY1 ankyrin repeat and FYVE domain containing 1 -2.0092
FAM111A family with sequence similarity 111, member A -2.00899
CENPX centromere protein X -2.00696
PHB1 prohibitin 1 -2.00289
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.00216