CRCGN014_HEPG2_24H:M18 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_24H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.63463
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.42654
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.0547
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.74694
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.41682
|
|
MAP7
|
microtubule-associated protein 7
|
3.92123
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.87197
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.57054
|
|
IDE
|
insulin-degrading enzyme
|
3.45062
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.37836
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.96068
|
|
SATB1
|
SATB homeobox 1
|
2.80882
|
|
CHN1
|
chimerin 1
|
2.7269
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.61922
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.55945
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.54253
|
|
ANTKMT
|
adenine nucleotide translocase lysine methyltransferase
|
2.35393
|
|
GATA2
|
GATA binding protein 2
|
2.24335
|
|
CHEK2
|
checkpoint kinase 2
|
2.14916
|
|
MINPP1
|
multiple inositol-polyphosphate phosphatase 1
|
2.01711
|
|
PRPS2
|
phosphoribosyl pyrophosphate synthetase 2
|
2.00252
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-5.29547
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.09572
|
|
GOLT1B
|
golgi transport 1B
|
-4.97139
|
|
LDHD
|
lactate dehydrogenase D
|
-4.66631
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.62788
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.5377
|
|
TLR4
|
toll-like receptor 4
|
-4.21165
|
|
CD320
|
CD320 molecule
|
-3.91329
|
|
WASHC4
|
WASH complex subunit 4
|
-3.64178
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.23403
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.13755
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.76862
|
|
TCTN1
|
tectonic family member 1
|
-2.71921
|
|
CCNB2
|
cyclin B2
|
-2.67158
|
|
SLC15A3
|
solute carrier family 15 (oligopeptide transporter), member 3
|
-2.48825
|
|
ZW10
|
zw10 kinetochore protein
|
-2.31043
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.19433
|
|
CLEC7A
|
C-type lectin domain family 7, member A
|
-2.10353
|
|
CDC50A
|
cell division cycle 50 P4-ATPase accessory subunit A
|
-2.0849
|
|
SLC9A5
|
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
|
-2.07803
|
