CRCGN014_HEPG2_24H:M19 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_24H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
7.15853
|
|
MYLK
|
myosin light chain kinase
|
5.10144
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.98081
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.92083
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.7902
|
|
LCN2
|
lipocalin 2
|
4.51352
|
|
CRTAP
|
cartilage associated protein
|
4.33752
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
4.04632
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.10665
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.94204
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.77608
|
|
CTSL
|
cathepsin L
|
2.56819
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.51341
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.40623
|
|
CZIB
|
CXXC motif containing zinc binding protein
|
2.29222
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.22958
|
|
HSPB1
|
heat shock 27kDa protein 1
|
2.03551
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-6.35441
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.43825
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-5.27542
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.06511
|
|
HMG20B
|
high mobility group 20B
|
-4.92719
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.0676
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.65033
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.46064
|
|
MAGEA4
|
melanoma antigen family A4
|
-2.71223
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.6485
|
|
GNAS
|
GNAS complex locus
|
-2.62866
|
|
GDF15
|
growth differentiation factor 15
|
-2.61187
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-2.57246
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.40964
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.29794
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.27727
|
|
NISCH
|
nischarin
|
-2.27024
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.23248
|
|
PLK1
|
polo-like kinase 1
|
-2.20069
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.18526
|
|
SEMG2
|
semenogelin II
|
-2.16609
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.15041
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.12281
|
|
GAGE1
|
G antigen 1
|
-2.02846
|
|
LDHD
|
lactate dehydrogenase D
|
-2.02612
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.01611
|
