CRCGN014_HEPG2_24H:M20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iodoform 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN014_HEPG2_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 5.84813
CHN1 chimerin 1 5.27951
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 5.10276
MAP7 microtubule-associated protein 7 4.67322
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.66691
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.80385
CYCS cytochrome c, somatic 3.40374
CIAO3 cytosolic iron-sulfur assembly component 3 3.31473
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.23228
LCN2 lipocalin 2 3.19775
RPP38 ribonuclease P/MRP 38kDa subunit 2.90454
NOTCH1 notch 1 2.8614
PEX11A peroxisomal biogenesis factor 11 alpha 2.74338
GARRE1 granule associated Rac and RHOG effector 1 2.61797
PNKP polynucleotide kinase 3'-phosphatase 2.43181
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.3241
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.24524
PPARG peroxisome proliferator-activated receptor gamma 2.20017
DENND2D DENN/MADD domain containing 2D 2.14584
PRKCH protein kinase C, eta 2.10949
NPDC1 neural proliferation, differentiation and control, 1 2.07003
GSTZ1 glutathione S-transferase zeta 1 2.04271

decreased expression

Symbol Name Standardized Value
FAIM Fas apoptotic inhibitory molecule -3.69718
DUSP6 dual specificity phosphatase 6 -3.57713
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.57648
DNM1L dynamin 1-like -2.90715
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.8711
VDAC1 voltage-dependent anion channel 1 -2.74128
PCNA proliferating cell nuclear antigen -2.68536
TOR1A torsin family 1, member A (torsin A) -2.45369
FASTKD5 FAST kinase domains 5 -2.41455
ICAM3 intercellular adhesion molecule 3 -2.34987
DDIT4 DNA-damage-inducible transcript 4 -2.20253
RAI14 retinoic acid induced 14 -2.15646
EGF epidermal growth factor -2.00978