CRCGN014_HEPG2_24H:M22 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_24H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
8.16957
|
|
UBQLN2
|
ubiquilin 2
|
7.99264
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.11928
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.95251
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.17983
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.11348
|
|
MYLK
|
myosin light chain kinase
|
4.01507
|
|
SFTPB
|
surfactant protein B
|
3.63066
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.58652
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.43842
|
|
MOK
|
MOK protein kinase
|
3.07166
|
|
HOXA10
|
homeobox A10
|
3.04048
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.83852
|
|
NOTCH1
|
notch 1
|
2.77629
|
|
STXBP1
|
syntaxin binding protein 1
|
2.71551
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.57209
|
|
GATA2
|
GATA binding protein 2
|
2.32998
|
|
BFAR
|
bifunctional apoptosis regulator
|
2.23482
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.55331
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.59376
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.32251
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.20803
|
|
TLR4
|
toll-like receptor 4
|
-3.84817
|
|
LDHD
|
lactate dehydrogenase D
|
-3.40854
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.40106
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.03427
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.87365
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.73865
|
|
EGF
|
epidermal growth factor
|
-2.61391
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.53735
|
|
EFCAB6
|
EF-hand calcium binding domain 6
|
-2.53342
|
|
TMEM97
|
transmembrane protein 97
|
-2.33357
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.26265
|
|
RNF167
|
ring finger protein 167
|
-2.2522
|
|
MTOR
|
mechanistic target of rapamycin (serine/threonine kinase)
|
-2.23457
|
|
TMC5
|
transmembrane channel-like 5
|
-2.2142
|
|
DDB1
|
damage-specific DNA binding protein 1, 127kDa
|
-2.21221
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.16249
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.13175
|
|
TSGA10
|
testis specific, 10
|
-2.1282
|
|
PSG11
|
pregnancy specific beta-1-glycoprotein 11
|
-2.07916
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.07577
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.0661
|
|
SEMA3E
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
|
-2.03445
|
