CRCGN014_HEPG2_24H:M24 Gene Set
Genes
30 genes differentially expressed following the CRCGN014_HEPG2_24H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.03251
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.97686
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.65687
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.57158
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.33877
|
|
MYLK
|
myosin light chain kinase
|
4.04085
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.94693
|
|
IDE
|
insulin-degrading enzyme
|
3.66743
|
|
EGF
|
epidermal growth factor
|
3.39203
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.03756
|
|
KIFBP
|
kinesin family binding protein
|
2.80439
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.53016
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.49164
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.43751
|
|
SCGB1D2
|
secretoglobin, family 1D, member 2
|
2.15043
|
|
CHEK2
|
checkpoint kinase 2
|
2.13012
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.10688
|
|
DMTF1
|
cyclin D binding myb-like transcription factor 1
|
2.0212
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-4.1283
|
|
TLR4
|
toll-like receptor 4
|
-3.51179
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.02133
|
|
GDF15
|
growth differentiation factor 15
|
-2.63509
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.56344
|
|
PPY
|
pancreatic polypeptide
|
-2.45546
|
|
RPS5
|
ribosomal protein S5
|
-2.38553
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.33705
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.2743
|
|
MALT1
|
MALT1 paracaspase
|
-2.1147
|
|
GNAS
|
GNAS complex locus
|
-2.09794
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.06162
|
