CRCGN014_HEPG2_24H:N02 Gene Set
Genes
38 genes differentially expressed following the CRCGN014_HEPG2_24H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
7.17455
|
|
CBR3
|
carbonyl reductase 3
|
6.45212
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.86044
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.65443
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
5.17591
|
|
MAP7
|
microtubule-associated protein 7
|
5.01842
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.32648
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.32069
|
|
GPATCH8
|
G patch domain containing 8
|
3.25447
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.12157
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.07627
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.00492
|
|
NOTCH1
|
notch 1
|
2.99638
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.97227
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.92101
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.81743
|
|
JADE2
|
jade family PHD finger 2
|
2.77446
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.67518
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.64619
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.55828
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.5257
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.44372
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.30951
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.19184
|
|
CCNA1
|
cyclin A1
|
2.00938
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB1
|
cyclin B1
|
-6.28048
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.36906
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.31076
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.1076
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.41649
|
|
ZNF586
|
zinc finger protein 586
|
-3.22922
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.12292
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.11599
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.04963
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.84166
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.50743
|
|
ALPK1
|
alpha-kinase 1
|
-2.02443
|
|
LCMT2
|
leucine carboxyl methyltransferase 2
|
-2.00437
|
