CRCGN014_HEPG2_24H:N06 Gene Set
Genes
37 genes differentially expressed following the CRCGN014_HEPG2_24H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
7.97324
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.18726
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.98196
|
|
ABHD6
|
abhydrolase domain containing 6
|
5.25701
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.66559
|
|
PIH1D1
|
PIH1 domain containing 1
|
3.56683
|
|
CHEK2
|
checkpoint kinase 2
|
3.54909
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.04092
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.00762
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.91851
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.86715
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.44155
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.37703
|
|
MAP7
|
microtubule-associated protein 7
|
2.31278
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.25133
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.15224
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.03042
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.022
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.19485
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-5.22527
|
|
RNF167
|
ring finger protein 167
|
-3.26116
|
|
TLR4
|
toll-like receptor 4
|
-3.23285
|
|
GNAS
|
GNAS complex locus
|
-3.15629
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.08212
|
|
CD320
|
CD320 molecule
|
-3.00188
|
|
CDC20
|
cell division cycle 20
|
-2.93799
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.68326
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.58827
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.56228
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.4893
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.24951
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.18806
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.17144
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.12792
|
|
PCBP1
|
poly(rC) binding protein 1
|
-2.08456
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.07501
|
|
INPP5A
|
inositol polyphosphate-5-phosphatase, 40kDa
|
-2.05198
|
