CRCGN014_HEPG2_24H:N10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sodium (e)-4-hydroxy-3-((4-sulfonatonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonate 21.89 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN014_HEPG2_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 8.28635
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.79279
UBQLN2 ubiquilin 2 4.95202
C2CD2 C2 calcium-dependent domain containing 2 3.66392
HLA-DRA major histocompatibility complex, class II, DR alpha 3.30328
ATP11B ATPase, class VI, type 11B 3.17017
ZNF589 zinc finger protein 589 2.77076
GSTZ1 glutathione S-transferase zeta 1 2.5584
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.42106
TIAM1 T-cell lymphoma invasion and metastasis 1 2.14017
CHN1 chimerin 1 2.115
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.00325

decreased expression

Symbol Name Standardized Value
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -4.34395
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.30656
ZNF586 zinc finger protein 586 -3.63962
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.85906
ADI1 acireductone dioxygenase 1 -2.16797