CRCGN014_HEPG2_24H:N11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aroclor 1016 38.8 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN014_HEPG2_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ATP11B ATPase, class VI, type 11B 6.06392
LCN2 lipocalin 2 3.49659
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.49395
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.3347
CHMP6 charged multivesicular body protein 6 3.07663
PRKCH protein kinase C, eta 2.74846
LOC122526780 uncharacterized LOC122526780 2.74743
STK10 serine/threonine kinase 10 2.70606
KIF20A kinesin family member 20A 2.58363
CCNF cyclin F 2.51944
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.42747
BIRC2 baculoviral IAP repeat containing 2 2.38928
PNKP polynucleotide kinase 3'-phosphatase 2.30205
ADGRE5 adhesion G protein-coupled receptor E5 2.30009
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.26929
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.23494
KIFBP kinesin family binding protein 2.10494

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.22423
GTPBP8 GTP-binding protein 8 (putative) -7.12467
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.61481
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -4.55481
TLCD3A TLC domain containing 3A -4.49305
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.2364
CDC20 cell division cycle 20 -4.03618
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.31675
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.92429
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.79784
CD320 CD320 molecule -2.73627
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.31094
WASHC4 WASH complex subunit 4 -2.30657
LDHD lactate dehydrogenase D -2.30375