CRCGN014_HEPG2_24H:N13 Gene Set
Genes
31 genes differentially expressed following the CRCGN014_HEPG2_24H:N13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
5.15105
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.69222
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.39681
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.35456
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.76122
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.65162
|
|
JADE2
|
jade family PHD finger 2
|
2.61862
|
|
NOTCH1
|
notch 1
|
2.60508
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.4267
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.35434
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.29304
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.18735
|
|
SFTPB
|
surfactant protein B
|
2.16385
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.13947
|
|
HEBP1
|
heme binding protein 1
|
2.09558
|
|
RAI14
|
retinoic acid induced 14
|
2.03832
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-5.35326
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.26352
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.26102
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.23847
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.18119
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.15707
|
|
CDC20
|
cell division cycle 20
|
-3.09352
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.06938
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.90275
|
|
DSG2
|
desmoglein 2
|
-2.87272
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.73672
|
|
CCNB1
|
cyclin B1
|
-2.40366
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.31347
|
|
GDF15
|
growth differentiation factor 15
|
-2.21865
|
|
ZNF586
|
zinc finger protein 586
|
-2.08171
|
