CRCGN014_HEPG2_24H:N14 Gene Set
Genes
53 genes differentially expressed following the CRCGN014_HEPG2_24H:N14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.48078
|
|
MAP7
|
microtubule-associated protein 7
|
6.44243
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.6861
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.35415
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.13216
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.12527
|
|
CCNA1
|
cyclin A1
|
3.67275
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.41299
|
|
FZD7
|
frizzled class receptor 7
|
3.21286
|
|
MYLK
|
myosin light chain kinase
|
3.13577
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.10466
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.08043
|
|
CYCS
|
cytochrome c, somatic
|
2.83614
|
|
CBR3
|
carbonyl reductase 3
|
2.63029
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.54731
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.51276
|
|
JADE2
|
jade family PHD finger 2
|
2.36119
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.31632
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.29941
|
|
PHF10
|
PHD finger protein 10
|
2.23465
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.09505
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.0341
|
|
DBNDD2
|
dysbindin (dystrobrevin binding protein 1) domain containing 2
|
2.02256
|
|
CHRM3
|
cholinergic receptor, muscarinic 3
|
2.00837
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.88592
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-5.30082
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.26915
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.08121
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.74479
|
|
NUP85
|
nucleoporin 85kDa
|
-3.71922
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.68402
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.37921
|
|
ZNF586
|
zinc finger protein 586
|
-3.35848
|
|
GDF15
|
growth differentiation factor 15
|
-3.28914
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.28914
|
|
CDC20
|
cell division cycle 20
|
-3.24321
|
|
DNM1L
|
dynamin 1-like
|
-3.21339
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.08859
|
|
CCNB2
|
cyclin B2
|
-3.0668
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.95308
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.77518
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.67597
|
|
APOE
|
apolipoprotein E
|
-2.64226
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.58885
|
|
WASHC4
|
WASH complex subunit 4
|
-2.55359
|
|
TLR4
|
toll-like receptor 4
|
-2.5179
|
|
EGF
|
epidermal growth factor
|
-2.50603
|
|
REEP5
|
receptor accessory protein 5
|
-2.44118
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.44073
|
|
HMG20B
|
high mobility group 20B
|
-2.29588
|
|
KCTD2
|
potassium channel tetramerization domain containing 2
|
-2.11786
|
|
CCNB1
|
cyclin B1
|
-2.09661
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.06797
|
