CRCGN014_HEPG2_24H:N15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description curcumin 20.63 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

446 genes differentially expressed following the CRCGN014_HEPG2_24H:N15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 9.92426
HMOX1 heme oxygenase 1 8.70357
KLHL21 kelch-like family member 21 7.71148
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 6.96245
FOSL1 FOS-like antigen 1 6.80518
ALAS1 5'-aminolevulinate synthase 1 6.02236
TXNRD1 thioredoxin reductase 1 5.90386
SQSTM1 sequestosome 1 5.56335
CBR1 carbonyl reductase 1 5.51923
TBPL1 TBP-like 1 5.41271
EGR1 early growth response 1 5.1807
UBQLN2 ubiquilin 2 5.06455
KEAP1 kelch-like ECH-associated protein 1 4.95556
CDPF1 cysteine-rich, DPF motif domain containing 1 4.79083
BIRC2 baculoviral IAP repeat containing 2 4.7855
HSPA1A heat shock 70kDa protein 1A 4.78486
LCN2 lipocalin 2 4.67814
H2BC12 H2B clustered histone 12 4.5304
CBR3 carbonyl reductase 3 4.4788
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.37996
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.23548
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.22026
TRIB3 tribbles pseudokinase 3 4.15606
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 4.07584
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 4.05533
MSRA methionine sulfoxide reductase A 4.03428
H2BC21 H2B clustered histone 21 3.98424
GOLT1B golgi transport 1B 3.93887
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.92884
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.89859
MCOLN1 mucolipin 1 3.84161
FASTKD5 FAST kinase domains 5 3.82058
PPIE peptidylprolyl isomerase E (cyclophilin E) 3.76322
EAPP E2F-associated phosphoprotein 3.71066
KDM3A lysine (K)-specific demethylase 3A 3.70859
ZFP36 ZFP36 ring finger protein 3.6864
CDK7 cyclin-dependent kinase 7 3.67953
TIMP2 TIMP metallopeptidase inhibitor 2 3.66227
NMU neuromedin U 3.58408
CHEK1 checkpoint kinase 1 3.55604
RBKS ribokinase 3.53594
TERF2IP telomeric repeat binding factor 2, interacting protein 3.52896
FRS2 fibroblast growth factor receptor substrate 2 3.50213
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.45042
DDIT4 DNA-damage-inducible transcript 4 3.39082
UFD1 ubiquitin recognition factor in ER associated degradation 1 3.389
TEX10 testis expressed 10 3.37148
TESK1 testis-specific kinase 1 3.3485
DNM1L dynamin 1-like 3.33639
TMEM50A transmembrane protein 50A 3.31533
SMAD3 SMAD family member 3 3.21095
FAIM Fas apoptotic inhibitory molecule 3.2061
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.20536
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.20256
TUBB6 tubulin, beta 6 class V 3.15085
LOC128125814 uncharacterized LOC128125814 3.1486
RNASE7 ribonuclease, RNase A family, 7 3.10905
TM9SF2 transmembrane 9 superfamily member 2 3.10624
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 3.05
INPP1 inositol polyphosphate-1-phosphatase 3.04701
FOXO4 forkhead box O4 2.98358
PRKCQ protein kinase C, theta 2.9683
EMC3 ER membrane protein complex subunit 3 2.96609
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.94282
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.94095
IER3 immediate early response 3 2.9391
NUP58 nucleoporin 58 2.92964
PYGO1 pygopus family PHD finger 1 2.91596
LYN LYN proto-oncogene, Src family tyrosine kinase 2.91139
OSER1 oxidative stress responsive serine-rich 1 2.87826
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.85002
ECD ecdysoneless homolog (Drosophila) 2.83734
CLK3 CDC-like kinase 3 2.82275
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.82068
MTMR2 myotubularin related protein 2 2.82067
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.80687
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.77826
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.76278
NPDC1 neural proliferation, differentiation and control, 1 2.70575
TBC1D15 TBC1 domain family, member 15 2.6765
HTRA1 HtrA serine peptidase 1 2.67126
EED embryonic ectoderm development 2.66554
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.65934
CYTH2 cytohesin 2 2.64928
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.6492
MAP7D1 MAP7 domain containing 1 2.64914
CTSD cathepsin D 2.62907
STX1A syntaxin 1A (brain) 2.61995
CIAO3 cytosolic iron-sulfur assembly component 3 2.61217
ATP11B ATPase, class VI, type 11B 2.57574
YPEL5 yippee-like 5 (Drosophila) 2.55903
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.55895
PNKP polynucleotide kinase 3'-phosphatase 2.54331
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.5416
KDM5A lysine (K)-specific demethylase 5A 2.53069
TRIM16 tripartite motif containing 16 2.52757
OSGIN1 oxidative stress induced growth inhibitor 1 2.5166
ATF3 activating transcription factor 3 2.50321
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 2.49728
FAM53C family with sequence similarity 53, member C 2.4848
ZNF394 zinc finger protein 394 2.477
TUFT1 tuftelin 1 2.47458
YAP1 Yes-associated protein 1 2.4643
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.45068
SDF2 stromal cell-derived factor 2 2.45053
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.44855
ZW10 zw10 kinetochore protein 2.44718
THUMPD2 THUMP domain containing 2 2.43999
RAB9A RAB9A, member RAS oncogene family 2.43949
MYNN myoneurin 2.42012
LRP10 low density lipoprotein receptor-related protein 10 2.41431
H2AC6 H2A clustered histone 6 2.41337
IST1 increased sodium tolerance 1 homolog (yeast) 2.40992
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.40347
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.40034
HLA-DRA major histocompatibility complex, class II, DR alpha 2.39905
NLRP2B NLR family pyrin domain containing 2B 2.39622
TALDO1 transaldolase 1 2.38593
TFG TRK-fused gene 2.38165
CNPY3 canopy FGF signaling regulator 3 2.36608
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.36572
HSPA1B heat shock 70kDa protein 1B 2.35627
FOXD1 forkhead box D1 2.35261
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.35107
RNF25 ring finger protein 25 2.35002
CARMIL1 capping protein regulator and myosin 1 linker 1 2.32599
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.30722
RASAL2 RAS protein activator like 2 2.30625
SMIM40 small integral membrane protein 40 2.30357
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.30302
PCDHB16 protocadherin beta 16 2.30047
TES testin LIM domain protein 2.29892
LARP6 La ribonucleoprotein domain family, member 6 2.29389
UFM1 ubiquitin-fold modifier 1 2.28453
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.27583
PPARG peroxisome proliferator-activated receptor gamma 2.2658
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.26398
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.25859
LIN37 lin-37 DREAM MuvB core complex component 2.25848
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.25523
THSD1 thrombospondin, type I, domain containing 1 2.24987
PFDN1 prefoldin subunit 1 2.24869
GPC1 glypican 1 2.24144
ZSCAN26 zinc finger and SCAN domain containing 26 2.2369
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.23305
FAM200C family with sequence similarity 200 member C 2.23287
ST14 suppression of tumorigenicity 14 (colon carcinoma) 2.23238
RRAGC Ras-related GTP binding C 2.22906
RBM22 RNA binding motif protein 22 2.21276
GTF2B general transcription factor IIB 2.21237
TICAM1 toll-like receptor adaptor molecule 1 2.18892
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.18442
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.17393
RPL39L ribosomal protein L39-like 2.17273
BCL7B B-cell CLL/lymphoma 7B 2.16846
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.16557
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.16343
COL17A1 collagen, type XVII, alpha 1 2.15318
PFN2 profilin 2 2.14925
AKR1C3 aldo-keto reductase family 1, member C3 2.14594
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.14579
DERL2 derlin 2 2.14577
BAG3 BCL2-associated athanogene 3 2.1419
RUSC2 RUN and SH3 domain containing 2 2.14162
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.13776
DIPK1A divergent protein kinase domain 1A 2.13775
WDR76 WD repeat domain 76 2.13696
KLHL4 kelch-like family member 4 2.13287
SSX1 synovial sarcoma, X breakpoint 1 2.13229
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 2.1321
CNPY4 canopy FGF signaling regulator 4 2.13208
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.11931
YME1L1 YME1-like 1 ATPase 2.11613
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.11577
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.11371
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.11315
DENND4C DENN/MADD domain containing 4C 2.11146
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.11
IFRD1 interferon-related developmental regulator 1 2.10889
TRIB1 tribbles pseudokinase 1 2.1051
TFIP11 tuftelin interacting protein 11 2.10126
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 2.09921
AFF4 AF4/FMR2 family, member 4 2.09322
H1-2 H1.2 linker histone, cluster member 2.09063
TTC1 tetratricopeptide repeat domain 1 2.08645
PROCR protein C receptor, endothelial 2.08332
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 2.08173
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.08104
NUCB2 nucleobindin 2 2.077
ZNF804A zinc finger protein 804A 2.0764
USP3 ubiquitin specific peptidase 3 2.07308
TUBA4A tubulin, alpha 4a 2.06895
LGMN legumain 2.06727
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.06707
EPHA3 EPH receptor A3 2.06438
LMBRD1 LMBR1 domain containing 1 2.06405
GBA1 glucosylceramidase beta 1 2.06359
ASB7 ankyrin repeat and SOCS box containing 7 2.06353
RBM7 RNA binding motif protein 7 2.06087
GCLM glutamate-cysteine ligase, modifier subunit 2.0582
BUD31 BUD31 homolog (S. cerevisiae) 2.05816
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 2.05605
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.05571
KITLG KIT ligand 2.05468
PHTF1 putative homeodomain transcription factor 1 2.0502
NOTCH1 notch 1 2.04911
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 2.04711
PTK2 protein tyrosine kinase 2 2.04673
UVRAG UV radiation resistance associated 2.0453
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.04465
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.04416
PIR pirin (iron-binding nuclear protein) 2.04363
BACE2 beta-site APP-cleaving enzyme 2 2.04028
GPATCH8 G patch domain containing 8 2.03862
SOWAHC sosondowah ankyrin repeat domain family member C 2.03489
CDKL3 cyclin-dependent kinase-like 3 2.0298
ANXA2 annexin A2 2.02849
NME8 NME/NM23 family member 8 2.02539
AMOTL2 angiomotin like 2 2.02262
CLTA clathrin, light chain A 2.0214
IGF1R insulin-like growth factor 1 receptor 2.02009
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 2.01977
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.01672
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.0167
ZNF227 zinc finger protein 227 2.0153
PRR13 proline rich 13 2.01345
CRIPT cysteine-rich PDZ-binding protein 2.01148
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.00953
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.00947
TRIM36 tripartite motif containing 36 2.00427
FBXO7 F-box protein 7 2.00092

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -8.22607
B4GAT1 beta-1,4-glucuronyltransferase 1 -8.10903
PYCR1 pyrroline-5-carboxylate reductase 1 -7.39282
PCCB propionyl CoA carboxylase, beta polypeptide -7.39045
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -7.17273
HMGA2 high mobility group AT-hook 2 -6.96434
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.42775
GALE UDP-galactose-4-epimerase -6.11547
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.02623
CDC20 cell division cycle 20 -5.4789
PGM1 phosphoglucomutase 1 -5.37626
ISOC1 isochorismatase domain containing 1 -5.36954
TSPAN4 tetraspanin 4 -5.25391
INTS3 integrator complex subunit 3 -5.14355
RSU1 Ras suppressor protein 1 -5.01386
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -4.91951
CD320 CD320 molecule -4.88577
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.85703
PLK1 polo-like kinase 1 -4.72054
STK25 serine/threonine kinase 25 -4.64688
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.6435
TCTN1 tectonic family member 1 -4.58404
NIPSNAP1 nipsnap homolog 1 (C. elegans) -4.45739
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.44543
TPM1 tropomyosin 1 (alpha) -4.41449
HADH hydroxyacyl-CoA dehydrogenase -4.28043
STAP2 signal transducing adaptor family member 2 -4.26828
MYLK myosin light chain kinase -4.18349
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.17109
TOP2A topoisomerase (DNA) II alpha 170kDa -4.09514
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -4.07718
DSG2 desmoglein 2 -4.04836
CDK1 cyclin-dependent kinase 1 -3.99119
NNT nicotinamide nucleotide transhydrogenase -3.98395
MRPS2 mitochondrial ribosomal protein S2 -3.95354
CCNA2 cyclin A2 -3.86067
C5 complement component 5 -3.81959
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.80888
ICAM3 intercellular adhesion molecule 3 -3.8084
ENOPH1 enolase-phosphatase 1 -3.79338
UBE3C ubiquitin protein ligase E3C -3.79079
GAA glucosidase, alpha; acid -3.77884
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.75726
C2CD5 C2 calcium-dependent domain containing 5 -3.75349
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -3.72151
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.71362
CCDC86 coiled-coil domain containing 86 -3.68351
NT5DC2 5'-nucleotidase domain containing 2 -3.52473
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -3.50541
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.48775
ICAM1 intercellular adhesion molecule 1 -3.40578
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.38269
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.35964
MELK maternal embryonic leucine zipper kinase -3.35524
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.30731
CASP3 caspase 3, apoptosis-related cysteine peptidase -3.28314
EVL Enah/Vasp-like -3.27498
ETFB electron-transfer-flavoprotein, beta polypeptide -3.27453
COG2 component of oligomeric golgi complex 2 -3.24626
MTA1 metastasis associated 1 -3.22985
SOAT2 sterol O-acyltransferase 2 -3.21186
THAP11 THAP domain containing 11 -3.13256
CBR4 carbonyl reductase 4 -3.13229
ZNF318 zinc finger protein 318 -3.12975
TLR4 toll-like receptor 4 -3.12518
RFC2 replication factor C (activator 1) 2, 40kDa -3.11055
NISCH nischarin -3.10996
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.10528
PLS1 plastin 1 -3.10205
RUVBL1 RuvB-like AAA ATPase 1 -3.08286
LDHD lactate dehydrogenase D -3.07222
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.04739
HEATR1 HEAT repeat containing 1 -3.04037
ACAA1 acetyl-CoA acyltransferase 1 -3.03389
CDK4 cyclin-dependent kinase 4 -3.02356
PGAM4 phosphoglycerate mutase family member 4 -3.00413
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.9795
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.95983
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.94896
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.93576
MRPL12 mitochondrial ribosomal protein L12 -2.92577
LAP3 leucine aminopeptidase 3 -2.91661
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.91015
AURKB aurora kinase B -2.90875
PECR peroxisomal trans-2-enoyl-CoA reductase -2.9038
FGFR4 fibroblast growth factor receptor 4 -2.88548
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.88489
PFKL phosphofructokinase, liver -2.86783
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.83901
RPIA ribose 5-phosphate isomerase A -2.82855
ASGR2 asialoglycoprotein receptor 2 -2.82525
FHL2 four and a half LIM domains 2 -2.81846
TEDC2 tubulin epsilon and delta complex 2 -2.81579
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.80733
PSRC1 proline/serine-rich coiled-coil 1 -2.79949
ENTR1 endosome associated trafficking regulator 1 -2.78674
ASGR1 asialoglycoprotein receptor 1 -2.78643
STAMBP STAM binding protein -2.77872
GALK1 galactokinase 1 -2.77683
RAB4A RAB4A, member RAS oncogene family -2.77458
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.7635
HMG20B high mobility group 20B -2.75537
DCK deoxycytidine kinase -2.74356
USP6NL USP6 N-terminal like -2.7289
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.71419
AMT aminomethyltransferase -2.70279
WASHC5 WASH complex subunit 5 -2.67612
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.67039
CDKN2A cyclin-dependent kinase inhibitor 2A -2.63346
GAMT guanidinoacetate N-methyltransferase -2.62645
FBXL12 F-box and leucine-rich repeat protein 12 -2.61733
SIAH2 siah E3 ubiquitin protein ligase 2 -2.60492
ANKRD10 ankyrin repeat domain 10 -2.60482
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.60377
ASF1B anti-silencing function 1B histone chaperone -2.59722
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.59615
SLC66A2 solute carrier family 66 member 2 -2.59167
STMN1 stathmin 1 -2.58673
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.567
PXMP2 peroxisomal membrane protein 2, 22kDa -2.55068
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.54986
DNAAF2 dynein, axonemal, assembly factor 2 -2.52547
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.50918
LBR lamin B receptor -2.4989
TFB1M transcription factor B1, mitochondrial -2.49687
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.49412
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.48976
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.48447
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.48007
GLOD4 glyoxalase domain containing 4 -2.4638
TRAP1 TNF receptor-associated protein 1 -2.45318
TUBG1 tubulin, gamma 1 -2.4446
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.42431
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.42268
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.4135
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.413
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.36812
ELAVL1 ELAV like RNA binding protein 1 -2.33766
MRPL19 mitochondrial ribosomal protein L19 -2.33086
PCNA proliferating cell nuclear antigen -2.32742
AHSG alpha-2-HS-glycoprotein -2.32397
GTPBP3 GTP binding protein 3 (mitochondrial) -2.31289
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.30428
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.30343
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.28892
DHCR24 24-dehydrocholesterol reductase -2.27268
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.27157
HPD 4-hydroxyphenylpyruvate dioxygenase -2.27085
SHPK sedoheptulokinase -2.27062
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.25973
COG7 component of oligomeric golgi complex 7 -2.25816
RPS5 ribosomal protein S5 -2.2577
FKBP3 FK506 binding protein 3, 25kDa -2.25599
TFDP1 transcription factor Dp-1 -2.24976
FTCD formimidoyltransferase cyclodeaminase -2.24964
MYO5C myosin VC -2.24931
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.24873
NUP85 nucleoporin 85kDa -2.23504
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.22663
MGST2 microsomal glutathione S-transferase 2 -2.223
NUDCD3 NudC domain containing 3 -2.22063
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -2.22057
PAH phenylalanine hydroxylase -2.20502
APOA2 apolipoprotein A-II -2.2049
APOM apolipoprotein M -2.20266
TSPAN6 tetraspanin 6 -2.19993
COPS7B COP9 signalosome subunit 7B -2.18043
ANXA6 annexin A6 -2.17599
CCNB2 cyclin B2 -2.161
MBL2 mannose-binding lectin (protein C) 2, soluble -2.15922
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.12131
SEC23A Sec23 homolog A (S. cerevisiae) -2.1184
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.11824
AKR1D1 aldo-keto reductase family 1, member D1 -2.11802
RCL1 RNA terminal phosphate cyclase-like 1 -2.11467
CPOX coproporphyrinogen oxidase -2.11211
RABEPK Rab9 effector protein with kelch motifs -2.09725
HEATR3 HEAT repeat containing 3 -2.09337
CRLF1 cytokine receptor-like factor 1 -2.09002
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.08885
DNAAF5 dynein, axonemal, assembly factor 5 -2.07886
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -2.07635
LCAT lecithin-cholesterol acyltransferase -2.07422
LRRC20 leucine rich repeat containing 20 -2.06522
PYGL phosphorylase, glycogen, liver -2.0616
PUS1 pseudouridylate synthase 1 -2.06043
LIPC lipase, hepatic -2.06001
ANKRD17 ankyrin repeat domain 17 -2.05993
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.05983
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.05797
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.05425
NUP133 nucleoporin 133kDa -2.05241
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.05227
KLHDC2 kelch domain containing 2 -2.05183
AMBP alpha-1-microglobulin/bikunin precursor -2.05182
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.04963
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.04653
ZFYVE21 zinc finger, FYVE domain containing 21 -2.04516
BAHCC1 BAH domain and coiled-coil containing 1 -2.04471
PROX1 prospero homeobox 1 -2.04387
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.04375
KHK ketohexokinase (fructokinase) -2.04299
IFFO1 intermediate filament family orphan 1 -2.04137
FAAP100 FA core complex associated protein 100 -2.03024
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.02868
SAA4 serum amyloid A4, constitutive -2.02641
DHCR7 7-dehydrocholesterol reductase -2.025
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.0239
SH3D19 SH3 domain containing 19 -2.02334
MRS2 MRS2 magnesium transporter -2.02293
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.02264
PROS1 protein S (alpha) -2.00902
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.00457
S100A4 S100 calcium binding protein A4 -2.00418
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.00312