CRCGN014_HEPG2_24H:N18 Gene Set
Genes
39 genes differentially expressed following the CRCGN014_HEPG2_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
6.03649
|
|
MYLK
|
myosin light chain kinase
|
4.58103
|
|
LCN2
|
lipocalin 2
|
4.34324
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.47019
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.45085
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.39829
|
|
CCNA1
|
cyclin A1
|
3.39111
|
|
JADE2
|
jade family PHD finger 2
|
3.1214
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
3.05307
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
2.81847
|
|
NMU
|
neuromedin U
|
2.72049
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.56349
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
2.5224
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.49384
|
|
PRKCH
|
protein kinase C, eta
|
2.39587
|
|
HEBP1
|
heme binding protein 1
|
2.1938
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.11906
|
|
CSK
|
c-src tyrosine kinase
|
2.0866
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.00067
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.05907
|
|
CCDC86
|
coiled-coil domain containing 86
|
-5.15889
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.50107
|
|
CCNB2
|
cyclin B2
|
-4.21597
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.5593
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.52541
|
|
TLR4
|
toll-like receptor 4
|
-3.48384
|
|
SNX11
|
sorting nexin 11
|
-3.40303
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.4013
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.35843
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.13574
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.81685
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.59644
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.58366
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.46914
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.43902
|
|
ZW10
|
zw10 kinetochore protein
|
-2.22046
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.0802
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.02669
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.00806
|
