CRCGN014_HEPG2_24H:N19 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_24H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
6.70975
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.47868
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.96864
|
|
CYCS
|
cytochrome c, somatic
|
3.53797
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.48089
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.43264
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.30207
|
|
EGF
|
epidermal growth factor
|
2.82537
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.70991
|
|
MAP7
|
microtubule-associated protein 7
|
2.56091
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.49639
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.49218
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.46558
|
|
PREB
|
prolactin regulatory element binding
|
2.33985
|
|
ZNF589
|
zinc finger protein 589
|
2.31979
|
|
ACSM3
|
acyl-CoA synthetase medium-chain family member 3
|
2.09862
|
|
LYSET
|
lysosomal enzyme trafficking factor
|
2.02009
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.68017
|
|
GNAS
|
GNAS complex locus
|
-4.70655
|
|
CCNB2
|
cyclin B2
|
-4.435
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.71776
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.5885
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-3.39441
|
|
GOLT1B
|
golgi transport 1B
|
-3.21248
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.06742
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.05283
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.95101
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.49467
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.2735
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.27343
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.19333
|
|
MFAP4
|
microfibrillar-associated protein 4
|
-2.17963
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.13963
|
|
NANOS2
|
nanos homolog 2 (Drosophila)
|
-2.07268
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.06476
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.02489
|
