CRCGN014_HEPG2_24H:N20 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_24H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
7.81199
|
|
MAP7
|
microtubule-associated protein 7
|
5.5178
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.82569
|
|
PRR15L
|
proline rich 15-like
|
3.5313
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.3785
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.07934
|
|
FPGS
|
folylpolyglutamate synthase
|
3.05362
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.01664
|
|
CHEK2
|
checkpoint kinase 2
|
2.88821
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.78119
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.40219
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.3904
|
|
ARB2A
|
ARB2 cotranscriptional regulator A
|
2.31356
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.27692
|
|
STXBP2
|
syntaxin binding protein 2
|
2.20857
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.16599
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.12644
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.1165
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNM1L
|
dynamin 1-like
|
-5.28805
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.87753
|
|
CDC20
|
cell division cycle 20
|
-4.56401
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.59179
|
|
ZNF586
|
zinc finger protein 586
|
-3.43792
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.29432
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.09342
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.06109
|
|
WASHC4
|
WASH complex subunit 4
|
-2.8989
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.58401
|
|
GNAS
|
GNAS complex locus
|
-2.49073
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.35994
|
|
ZW10
|
zw10 kinetochore protein
|
-2.12492
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.05519
|
|
CCNB2
|
cyclin B2
|
-2.05112
|
