CRCGN014_HEPG2_24H:N22 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_24H:N22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
9.3684
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.49486
|
|
UBQLN2
|
ubiquilin 2
|
4.47598
|
|
EVL
|
Enah/Vasp-like
|
4.1842
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.49236
|
|
HEBP1
|
heme binding protein 1
|
3.42523
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
3.3508
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.34658
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.84973
|
|
CCNF
|
cyclin F
|
2.80904
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.55004
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.52394
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.4455
|
|
CHN1
|
chimerin 1
|
2.42373
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.32144
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.20971
|
|
GPATCH8
|
G patch domain containing 8
|
2.17998
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.14451
|
|
NUP37
|
nucleoporin 37kDa
|
2.13931
|
|
STXBP2
|
syntaxin binding protein 2
|
2.10989
|
|
DMAP1
|
DNA methyltransferase 1 associated protein 1
|
2.08896
|
|
MEST
|
mesoderm specific transcript
|
2.07068
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.10699
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.89013
|
|
CD320
|
CD320 molecule
|
-4.3944
|
|
THAP11
|
THAP domain containing 11
|
-4.1221
|
|
GNAS
|
GNAS complex locus
|
-3.94252
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.93781
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.85899
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.7759
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.43631
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.03667
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.86823
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.66183
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.64098
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.6116
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.4998
|
|
BNIP3L
|
BCL2/adenovirus E1B 19kDa interacting protein 3-like
|
-2.42021
|
|
AFF4
|
AF4/FMR2 family, member 4
|
-2.3752
|
|
DPY19L4
|
dpy-19-like 4 (C. elegans)
|
-2.21276
|
|
KLF3
|
Kruppel-like factor 3 (basic)
|
-2.09372
|
|
CCR5
|
chemokine (C-C motif) receptor 5 (gene/pseudogene)
|
-2.07692
|
|
DCHS2
|
dachsous cadherin-related 2
|
-2.01038
|