CRCGN014_HEPG2_24H:O04 Gene Set
Genes
50 genes differentially expressed following the CRCGN014_HEPG2_24H:O04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.58255
|
|
NOTCH1
|
notch 1
|
3.75304
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.62518
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.19138
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
3.15857
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.09364
|
|
MYLK
|
myosin light chain kinase
|
3.05773
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.91495
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.74421
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.55237
|
|
STIMATE
|
STIM activating enhancer
|
2.55018
|
|
CHN1
|
chimerin 1
|
2.27893
|
|
SATB1
|
SATB homeobox 1
|
2.27641
|
|
NUP133
|
nucleoporin 133kDa
|
2.24107
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.17896
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.1658
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.16557
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.14999
|
|
PRR15L
|
proline rich 15-like
|
2.1318
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.02544
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.7715
|
|
LDHD
|
lactate dehydrogenase D
|
-6.58367
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-6.41989
|
|
TLR4
|
toll-like receptor 4
|
-5.25107
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.10959
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.47869
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.10286
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.00504
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.72649
|
|
DUSP6
|
dual specificity phosphatase 6
|
-3.5092
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.47994
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.31801
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.22788
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.16653
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.09525
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.81853
|
|
CCNB2
|
cyclin B2
|
-2.68963
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.60147
|
|
CCNB1
|
cyclin B1
|
-2.60095
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.38768
|
|
GIMAP4
|
GTPase, IMAP family member 4
|
-2.31489
|
|
VNN2
|
vanin 2
|
-2.22686
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.21577
|
|
SNX11
|
sorting nexin 11
|
-2.20507
|
|
HMOX2
|
heme oxygenase 2
|
-2.19621
|
|
EGF
|
epidermal growth factor
|
-2.18135
|
|
RXRG
|
retinoid X receptor, gamma
|
-2.08882
|
|
EDN1
|
endothelin 1
|
-2.07155
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.06225
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.02264
|
