CRCGN014_HEPG2_24H:O10 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_24H:O10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
4.92522
|
|
STK10
|
serine/threonine kinase 10
|
4.51653
|
|
CBR3
|
carbonyl reductase 3
|
4.43149
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
4.04259
|
|
CYCS
|
cytochrome c, somatic
|
3.97372
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.9057
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.5782
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.56471
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.45219
|
|
UBQLN2
|
ubiquilin 2
|
3.35288
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.34492
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.2777
|
|
EPN2
|
epsin 2
|
2.95235
|
|
NOTCH1
|
notch 1
|
2.84711
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.80825
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.62238
|
|
PCDHB11
|
protocadherin beta 11
|
2.53033
|
|
SATB1
|
SATB homeobox 1
|
2.22281
|
|
XYLT1
|
xylosyltransferase I
|
2.21629
|
|
TRIM9
|
tripartite motif containing 9
|
2.19308
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.14552
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.29174
|
|
TSPAN4
|
tetraspanin 4
|
-4.95923
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.70122
|
|
TLR4
|
toll-like receptor 4
|
-4.23774
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-4.2314
|
|
CCNB2
|
cyclin B2
|
-4.2016
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.99684
|
|
THAP11
|
THAP domain containing 11
|
-3.48976
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.33671
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.33186
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.18081
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.9696
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.57505
|
|
GTF3C4
|
general transcription factor IIIC, polypeptide 4, 90kDa
|
-2.5229
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.5085
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.45937
|
|
GNAS
|
GNAS complex locus
|
-2.45158
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.4394
|
|
PPP1R26
|
protein phosphatase 1, regulatory subunit 26
|
-2.34255
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.33185
|
|
ACP2
|
acid phosphatase 2, lysosomal
|
-2.23988
|
|
PFDN1
|
prefoldin subunit 1
|
-2.07097
|
|
NVL
|
nuclear VCP-like
|
-2.05853
|
