CRCGN014_HEPG2_24H:O13 Gene Set
Genes
34 genes differentially expressed following the CRCGN014_HEPG2_24H:O13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
5.56058
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.2566
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.97212
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.95717
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.85373
|
|
STIMATE
|
STIM activating enhancer
|
3.56755
|
|
MEF2C
|
myocyte enhancer factor 2C
|
3.5501
|
|
CYCS
|
cytochrome c, somatic
|
3.04631
|
|
MAP7
|
microtubule-associated protein 7
|
2.96272
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.95282
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.73312
|
|
TRIM13
|
tripartite motif containing 13
|
2.5378
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
2.394
|
|
FZD7
|
frizzled class receptor 7
|
2.37924
|
|
PRR15L
|
proline rich 15-like
|
2.36643
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.32567
|
|
TMEM109
|
transmembrane protein 109
|
2.21255
|
|
TEX2
|
testis expressed 2
|
2.15831
|
|
LCN2
|
lipocalin 2
|
2.15448
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-7.49554
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.33792
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-6.01624
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.36933
|
|
ZNF586
|
zinc finger protein 586
|
-4.56788
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.08153
|
|
LDHD
|
lactate dehydrogenase D
|
-3.7153
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.81522
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.47649
|
|
GDF15
|
growth differentiation factor 15
|
-2.47193
|
|
CCNB2
|
cyclin B2
|
-2.46241
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.33795
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.28677
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.19245
|
|
LYPLA1
|
lysophospholipase I
|
-2.15207
|
