CRCGN014_HEPG2_24H:O14 Gene Set
Genes
37 genes differentially expressed following the CRCGN014_HEPG2_24H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
4.98325
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.52167
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.35205
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.86341
|
|
EPHB2
|
EPH receptor B2
|
3.74905
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.61205
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.33896
|
|
MAP7
|
microtubule-associated protein 7
|
3.2783
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.25764
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.88024
|
|
KIFBP
|
kinesin family binding protein
|
2.81175
|
|
FZD7
|
frizzled class receptor 7
|
2.54382
|
|
PRR15L
|
proline rich 15-like
|
2.52144
|
|
JADE2
|
jade family PHD finger 2
|
2.4975
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.30585
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.22289
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.10048
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.06952
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.012
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.56531
|
|
GOLT1B
|
golgi transport 1B
|
-5.0298
|
|
THAP11
|
THAP domain containing 11
|
-4.82906
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.5872
|
|
CDC20
|
cell division cycle 20
|
-4.34596
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.22843
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.22032
|
|
OXSR1
|
oxidative stress responsive 1
|
-3.75373
|
|
ZNF586
|
zinc finger protein 586
|
-3.65354
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.49653
|
|
GNAS
|
GNAS complex locus
|
-2.99259
|
|
TLR4
|
toll-like receptor 4
|
-2.56591
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.53924
|
|
MTA1
|
metastasis associated 1
|
-2.3692
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.3212
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.14367
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.09457
|
|
RECQL
|
RecQ helicase-like
|
-2.03068
|
