CRCGN014_HEPG2_24H:O15 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SQOR
|
sulfide quinone oxidoreductase
|
5.07334
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.92343
|
|
HOXA10
|
homeobox A10
|
4.58304
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.3939
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.11178
|
|
STK10
|
serine/threonine kinase 10
|
4.04479
|
|
MAP7
|
microtubule-associated protein 7
|
4.02266
|
|
CCNF
|
cyclin F
|
2.70224
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.66573
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.65933
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.63298
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.44318
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.27659
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.24611
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.17104
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.14618
|
|
CCND2
|
cyclin D2
|
2.00511
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.91939
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.8745
|
|
GOLT1B
|
golgi transport 1B
|
-4.73181
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.54753
|
|
LDHD
|
lactate dehydrogenase D
|
-4.39186
|
|
THAP11
|
THAP domain containing 11
|
-4.36389
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.25417
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.70717
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.50239
|
|
SNX11
|
sorting nexin 11
|
-3.46354
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.25102
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.80379
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.6016
|
|
CAPNS1
|
calpain, small subunit 1
|
-2.30195
|
|
ZW10
|
zw10 kinetochore protein
|
-2.22007
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.21028
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.10324
|
|
SDHAF1
|
succinate dehydrogenase complex assembly factor 1
|
-2.06147
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.02726
|
