CRCGN014_HEPG2_24H:O17 Gene Set
Genes
23 genes differentially expressed following the CRCGN014_HEPG2_24H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.34416
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.12504
|
|
LCN2
|
lipocalin 2
|
4.09334
|
|
EPN2
|
epsin 2
|
3.92231
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.77653
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.44572
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.97713
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.30776
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.30598
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.10638
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.04074
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD320
|
CD320 molecule
|
-5.33303
|
|
CDC20
|
cell division cycle 20
|
-4.41035
|
|
LDHD
|
lactate dehydrogenase D
|
-4.17054
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.03032
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.33631
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.17608
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.95381
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.91212
|
|
TLR4
|
toll-like receptor 4
|
-2.66142
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.42285
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
-2.29142
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.00137
|
