CRCGN014_HEPG2_24H:O21 Gene Set
Genes
27 genes differentially expressed following the CRCGN014_HEPG2_24H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
5.8291
|
|
MYLK
|
myosin light chain kinase
|
5.16107
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.55606
|
|
PRR15L
|
proline rich 15-like
|
4.4297
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
4.07077
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.88929
|
|
IDE
|
insulin-degrading enzyme
|
3.33342
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.07254
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.7562
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.46674
|
|
CHN1
|
chimerin 1
|
2.18807
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.1299
|
|
AP1S2
|
adaptor-related protein complex 1, sigma 2 subunit
|
2.07826
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNM1L
|
dynamin 1-like
|
-4.60074
|
|
CDC20
|
cell division cycle 20
|
-4.559
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.40741
|
|
ZNF586
|
zinc finger protein 586
|
-4.40278
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.34349
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.32557
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.67866
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.48581
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.47547
|
|
GNAS
|
GNAS complex locus
|
-3.20481
|
|
TCTN1
|
tectonic family member 1
|
-2.3332
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.20913
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.1478
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.06401
|
