CRCGN014_HEPG2_24H:O24 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_24H:O24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.9339
|
|
GPATCH8
|
G patch domain containing 8
|
3.75805
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.63094
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.57487
|
|
CBR3
|
carbonyl reductase 3
|
3.47235
|
|
BLMH
|
bleomycin hydrolase
|
3.43079
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.29514
|
|
UBQLN2
|
ubiquilin 2
|
3.27696
|
|
RPL39L
|
ribosomal protein L39-like
|
3.11695
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.87863
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.78225
|
|
E2F2
|
E2F transcription factor 2
|
2.71443
|
|
MAP7
|
microtubule-associated protein 7
|
2.7111
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.44284
|
|
EVL
|
Enah/Vasp-like
|
2.38893
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.31533
|
|
CYCS
|
cytochrome c, somatic
|
2.30285
|
|
GATA3
|
GATA binding protein 3
|
2.29039
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.23322
|
|
S100A4
|
S100 calcium binding protein A4
|
2.15912
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.90208
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.35863
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.85611
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.79415
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.71888
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.46701
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.39788
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.27149
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.16883
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.08088
|
|
SCAND1
|
SCAN domain containing 1
|
-3.00676
|
|
ZNF586
|
zinc finger protein 586
|
-2.92897
|
|
EGF
|
epidermal growth factor
|
-2.89799
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.79986
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.76501
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.75434
|
|
COG4
|
component of oligomeric golgi complex 4
|
-2.74216
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.69037
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.66212
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.56852
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.56722
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.50069
|
|
HMG20B
|
high mobility group 20B
|
-2.43907
|
|
GNAS
|
GNAS complex locus
|
-2.41068
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.20556
|
|
RAI14
|
retinoic acid induced 14
|
-2.09818
|
|
GDF15
|
growth differentiation factor 15
|
-2.07856
|
