CRCGN014_HEPG2_24H:P06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isobutyraldehyde 40.8 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN014_HEPG2_24H:P06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.93547
LCN2 lipocalin 2 4.59447
RPP38 ribonuclease P/MRP 38kDa subunit 4.35174
EGF epidermal growth factor 4.25819
SQOR sulfide quinone oxidoreductase 4.04424
C2CD2 C2 calcium-dependent domain containing 2 3.8765
EPHB2 EPH receptor B2 3.79979
UBQLN2 ubiquilin 2 3.50313
HOXA10 homeobox A10 3.42082
GSTZ1 glutathione S-transferase zeta 1 3.1187
PMM2 phosphomannomutase 2 2.60815
USP6NL USP6 N-terminal like 2.51884
ZNF559-ZNF177 ZNF559-ZNF177 readthrough 2.41699
CHN1 chimerin 1 2.23554
SATB1 SATB homeobox 1 2.15275
MCM10 minichromosome maintenance complex component 10 2.10114
CERK ceramide kinase 2.05662

decreased expression

Symbol Name Standardized Value
NT5DC2 5'-nucleotidase domain containing 2 -4.63282
CCNB2 cyclin B2 -3.46531
GNAS GNAS complex locus -3.14216
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.12798
TLCD3A TLC domain containing 3A -2.8665
DERA deoxyribose-phosphate aldolase (putative) -2.48002
TLR4 toll-like receptor 4 -2.3283
EIF4A2 eukaryotic translation initiation factor 4A2 -2.04927
TRPS1 trichorhinophalangeal syndrome I -2.02754