CRCGN014_HEPG2_24H:P08 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_24H:P08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.80497
|
|
FZD7
|
frizzled class receptor 7
|
5.37881
|
|
MYLK
|
myosin light chain kinase
|
4.72887
|
|
UBQLN2
|
ubiquilin 2
|
4.31443
|
|
EVL
|
Enah/Vasp-like
|
4.17236
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.06494
|
|
HOXA10
|
homeobox A10
|
3.81245
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.51382
|
|
CBR3
|
carbonyl reductase 3
|
3.50104
|
|
CCNF
|
cyclin F
|
3.06981
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.59417
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.34357
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.16031
|
|
VGLL4
|
vestigial-like family member 4
|
2.13078
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.09431
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GOLT1B
|
golgi transport 1B
|
-7.17109
|
|
LDHD
|
lactate dehydrogenase D
|
-7.09252
|
|
CDC20
|
cell division cycle 20
|
-4.23067
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.08818
|
|
PEG10
|
paternally expressed 10
|
-3.61925
|
|
CCNB2
|
cyclin B2
|
-3.54312
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.46108
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.95891
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.92797
|
|
TLR4
|
toll-like receptor 4
|
-2.74968
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.71267
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.5924
|
|
RECQL
|
RecQ helicase-like
|
-2.53327
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.49021
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.4827
|
|
SNX11
|
sorting nexin 11
|
-2.4475
|
|
CHEK1
|
checkpoint kinase 1
|
-2.21834
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.19511
|
