CRCGN014_HEPG2_24H:P10 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:P10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
4.09229
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.01625
|
|
CCNF
|
cyclin F
|
3.76095
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.6845
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.47485
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.30654
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.15918
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.10363
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.8683
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.68379
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.67903
|
|
CYCS
|
cytochrome c, somatic
|
2.65824
|
|
SFTPB
|
surfactant protein B
|
2.65513
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.31596
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.14051
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.12564
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.85347
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.56072
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.4074
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.39012
|
|
GOLT1B
|
golgi transport 1B
|
-3.38464
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.37416
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.11954
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.05563
|
|
RNF167
|
ring finger protein 167
|
-2.78058
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.77414
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.77331
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-2.62871
|
|
BNIP3
|
BCL2/adenovirus E1B 19kDa interacting protein 3
|
-2.33096
|
|
TLR4
|
toll-like receptor 4
|
-2.28415
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.18143
|
|
DUSP6
|
dual specificity phosphatase 6
|
-2.12772
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.06802
|
|
ZNF586
|
zinc finger protein 586
|
-2.03224
|
|
LINS1
|
lines homolog 1
|
-2.00158
|
