CRCGN014_HEPG2_24H:P12 Gene Set
Genes
39 genes differentially expressed following the CRCGN014_HEPG2_24H:P12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
8.25148
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.48625
|
|
PRR15L
|
proline rich 15-like
|
5.3703
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.91565
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.79525
|
|
MAP7
|
microtubule-associated protein 7
|
4.37938
|
|
STIMATE
|
STIM activating enhancer
|
3.93327
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
3.72976
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.48499
|
|
RRAGA
|
Ras-related GTP binding A
|
3.45314
|
|
CBR3
|
carbonyl reductase 3
|
3.39141
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.27239
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.19716
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.08089
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.01613
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.93865
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.91291
|
|
CDC45
|
cell division cycle 45
|
2.47028
|
|
CRTAP
|
cartilage associated protein
|
2.46581
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.2687
|
|
CEACAM5
|
carcinoembryonic antigen-related cell adhesion molecule 5
|
2.25324
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.25024
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.22195
|
|
GPATCH8
|
G patch domain containing 8
|
2.15261
|
|
EVL
|
Enah/Vasp-like
|
2.04739
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-8.24378
|
|
TLR4
|
toll-like receptor 4
|
-4.33684
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.39032
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.29637
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-3.16422
|
|
RAI14
|
retinoic acid induced 14
|
-2.81299
|
|
EDN1
|
endothelin 1
|
-2.78064
|
|
EGF
|
epidermal growth factor
|
-2.67695
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
-2.61219
|
|
DNMT1
|
DNA (cytosine-5-)-methyltransferase 1
|
-2.55411
|
|
CCNB2
|
cyclin B2
|
-2.36423
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.23875
|
|
ZNF274
|
zinc finger protein 274
|
-2.05971
|
|
NEUROG1
|
neurogenin 1
|
-2.01675
|
