CRCGN014_HEPG2_24H:P13 Gene Set
Genes
32 genes differentially expressed following the CRCGN014_HEPG2_24H:P13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
7.20052
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.88786
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.89704
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.81246
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.76189
|
|
MYLK
|
myosin light chain kinase
|
3.74103
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.61124
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.59223
|
|
EGF
|
epidermal growth factor
|
3.57732
|
|
CBR3
|
carbonyl reductase 3
|
3.55551
|
|
CHN1
|
chimerin 1
|
3.40192
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.31318
|
|
MOK
|
MOK protein kinase
|
2.91312
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.78877
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.52718
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.43379
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.18746
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.16851
|
|
PFKL
|
phosphofructokinase, liver
|
2.00995
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.00449
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-6.14671
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.18606
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.64257
|
|
LDHD
|
lactate dehydrogenase D
|
-3.39914
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.31563
|
|
CAB39
|
calcium binding protein 39
|
-3.17159
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.83436
|
|
ZNF274
|
zinc finger protein 274
|
-2.63929
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.53745
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.38026
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.34347
|
|
ZMAT4
|
zinc finger, matrin-type 4
|
-2.02253
|
