CRCGN014_HEPG2_24H:P14 Gene Set
Genes
54 genes differentially expressed following the CRCGN014_HEPG2_24H:P14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PLS1
|
plastin 1
|
4.73713
|
|
MAP7
|
microtubule-associated protein 7
|
4.42643
|
|
LCN2
|
lipocalin 2
|
4.32209
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.17919
|
|
CHN1
|
chimerin 1
|
4.1676
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.8874
|
|
EPHB2
|
EPH receptor B2
|
3.27421
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.1296
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.99872
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.99635
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.9528
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.86577
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.83748
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.70222
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.41885
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.30863
|
|
GUCY2C
|
guanylate cyclase 2C
|
2.28632
|
|
CYCS
|
cytochrome c, somatic
|
2.24894
|
|
NEO1
|
neogenin 1
|
2.23319
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.14624
|
|
EPN2
|
epsin 2
|
2.09341
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.0765
|
|
RRAGA
|
Ras-related GTP binding A
|
2.06856
|
|
CDX1
|
caudal type homeobox 1
|
2.03723
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.03069
|
|
UBP1
|
upstream binding protein 1 (LBP-1a)
|
2.02125
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-5.2613
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.72308
|
|
GNAS
|
GNAS complex locus
|
-4.64715
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.49074
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.42285
|
|
TLR4
|
toll-like receptor 4
|
-4.28628
|
|
RNF167
|
ring finger protein 167
|
-3.9902
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.74735
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.69472
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.19519
|
|
HMG20B
|
high mobility group 20B
|
-2.89886
|
|
RAI14
|
retinoic acid induced 14
|
-2.81678
|
|
MFF
|
mitochondrial fission factor
|
-2.7523
|
|
CCNB2
|
cyclin B2
|
-2.37236
|
|
ZNF274
|
zinc finger protein 274
|
-2.35185
|
|
EGF
|
epidermal growth factor
|
-2.27655
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.2711
|
|
WASHC4
|
WASH complex subunit 4
|
-2.22616
|
|
NPIPB5
|
nuclear pore complex interacting protein family, member B5
|
-2.20458
|
|
GTF2E2
|
general transcription factor IIE, polypeptide 2, beta 34kDa
|
-2.1588
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
-2.08659
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.08235
|
|
EMSY
|
EMSY transcriptional repressor, BRCA2 interacting
|
-2.07659
|
|
ITM2B
|
integral membrane protein 2B
|
-2.0388
|
|
ZNF586
|
zinc finger protein 586
|
-2.03302
|
|
TEX10
|
testis expressed 10
|
-2.01636
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.00975
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.0075
|
