CRCGN014_HEPG2_24H:P15 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_24H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ATP11B
|
ATPase, class VI, type 11B
|
8.79414
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.66739
|
|
EGF
|
epidermal growth factor
|
4.47047
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.45592
|
|
NOTCH1
|
notch 1
|
4.3064
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.30623
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.82636
|
|
E2F2
|
E2F transcription factor 2
|
3.53141
|
|
SATB1
|
SATB homeobox 1
|
3.39721
|
|
SFTPB
|
surfactant protein B
|
3.33995
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.26327
|
|
CHN1
|
chimerin 1
|
3.13588
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.93143
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.79083
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.77216
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.58583
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.50389
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.39406
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.17354
|
|
PCDHB11
|
protocadherin beta 11
|
2.12012
|
|
TRMT13
|
tRNA methyltransferase 13 homolog (S. cerevisiae)
|
2.06437
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.05606
|
|
PRPF39
|
pre-mRNA processing factor 39
|
2.00494
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LAP3
|
leucine aminopeptidase 3
|
-4.57101
|
|
TLR4
|
toll-like receptor 4
|
-4.35729
|
|
CTSD
|
cathepsin D
|
-3.31455
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.20596
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.98497
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.98412
|
|
RAI14
|
retinoic acid induced 14
|
-2.93745
|
|
LDHD
|
lactate dehydrogenase D
|
-2.92828
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.9218
|
|
STX4
|
syntaxin 4
|
-2.90082
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.81863
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.81294
|
|
CCNB2
|
cyclin B2
|
-2.75634
|
|
CAMLG
|
calcium modulating ligand
|
-2.26095
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.21219
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.16937
|
|
ACTR3B
|
ARP3 actin-related protein 3 homolog B (yeast)
|
-2.15983
|
|
ZNRF2
|
zinc and ring finger 2, E3 ubiquitin protein ligase
|
-2.14947
|
|
CXADR
|
coxsackie virus and adenovirus receptor
|
-2.0666
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.05318
|
|
PPA1
|
pyrophosphatase (inorganic) 1
|
-2.043
|
