CRCGN014_HEPG2_24H:P17 Gene Set
Genes
54 genes differentially expressed following the CRCGN014_HEPG2_24H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
5.34006
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.04224
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.71505
|
|
RPL39L
|
ribosomal protein L39-like
|
4.62998
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.32291
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.14376
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.78386
|
|
GPATCH8
|
G patch domain containing 8
|
2.94639
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.93878
|
|
EGF
|
epidermal growth factor
|
2.73503
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.52056
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.481
|
|
EVL
|
Enah/Vasp-like
|
2.37754
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.27602
|
|
CHN1
|
chimerin 1
|
2.26168
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.24931
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.21141
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.15536
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.09317
|
|
FAM50A
|
family with sequence similarity 50, member A
|
2.08614
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.05979
|
|
PNRC2
|
proline-rich nuclear receptor coactivator 2
|
2.05287
|
|
PTGES3
|
prostaglandin E synthase 3 (cytosolic)
|
2.04669
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.04136
|
|
KIF20A
|
kinesin family member 20A
|
2.0172
|
|
ALDH9A1
|
aldehyde dehydrogenase 9 family, member A1
|
2.00636
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-6.33695
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.51434
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.51375
|
|
VAT1
|
vesicle amine transport 1
|
-4.03609
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.9691
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.81116
|
|
LDHD
|
lactate dehydrogenase D
|
-3.53167
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.21744
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.2101
|
|
TLR4
|
toll-like receptor 4
|
-3.17396
|
|
SNX11
|
sorting nexin 11
|
-2.98516
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.92015
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.80096
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.73896
|
|
FBXO7
|
F-box protein 7
|
-2.57916
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.5532
|
|
UPB1
|
ureidopropionase, beta
|
-2.48025
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.46972
|
|
EDN1
|
endothelin 1
|
-2.34196
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.23273
|
|
ACSM2A
|
acyl-CoA synthetase medium-chain family member 2A
|
-2.17631
|
|
CD58
|
CD58 molecule
|
-2.168
|
|
SMG1
|
SMG1 phosphatidylinositol 3-kinase-related kinase
|
-2.13341
|
|
CTSD
|
cathepsin D
|
-2.12334
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.05037
|
|
DPYS
|
dihydropyrimidinase
|
-2.04939
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.02331
|
|
SLC22A2
|
solute carrier family 22 (organic cation transporter), member 2
|
-2.01596
|
