CRCGN014_HEPG2_24H:P18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dichlorophenoxyacetic acid 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN014_HEPG2_24H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 6.03004
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.97927
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.53623
C2CD2 C2 calcium-dependent domain containing 2 4.39033
STIMATE STIM activating enhancer 4.3503
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.08362
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.85665
CCL2 chemokine (C-C motif) ligand 2 3.7972
MAP7 microtubule-associated protein 7 3.65121
GSTZ1 glutathione S-transferase zeta 1 2.83714
KIF20A kinesin family member 20A 2.68702
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.43245
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.37963
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.28672
KLHL9 kelch-like family member 9 2.28189
CCNF cyclin F 2.21109
LPAR2 lysophosphatidic acid receptor 2 2.17367
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.07624

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -4.23
LDHD lactate dehydrogenase D -4.12184
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.85795
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.82536
COG7 component of oligomeric golgi complex 7 -2.79946
CD58 CD58 molecule -2.65232
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.61066
TCEAL4 transcription elongation factor A (SII)-like 4 -2.16125
CLTB clathrin, light chain B -2.12999
FAIM Fas apoptotic inhibitory molecule -2.02751
PRPF4 pre-mRNA processing factor 4 -2.02538