CRCGN014_HEPG2_24H:P22 Gene Set
Genes
58 genes differentially expressed following the CRCGN014_HEPG2_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.76461
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.86329
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.15169
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.14881
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.09063
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.87498
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.73407
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.70753
|
|
CYCS
|
cytochrome c, somatic
|
3.56559
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.47087
|
|
NOTCH1
|
notch 1
|
3.41827
|
|
EPHA3
|
EPH receptor A3
|
3.32716
|
|
CHEK2
|
checkpoint kinase 2
|
3.13475
|
|
UBQLN2
|
ubiquilin 2
|
3.09565
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.01832
|
|
CCNF
|
cyclin F
|
2.91919
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.90082
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.81867
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.8083
|
|
HEBP1
|
heme binding protein 1
|
2.49607
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.43682
|
|
SATB1
|
SATB homeobox 1
|
2.40211
|
|
EPHB2
|
EPH receptor B2
|
2.38475
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.36356
|
|
RRAGA
|
Ras-related GTP binding A
|
2.33908
|
|
MAP7
|
microtubule-associated protein 7
|
2.22342
|
|
NUP133
|
nucleoporin 133kDa
|
2.14943
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.13819
|
|
INPPL1
|
inositol polyphosphate phosphatase-like 1
|
2.1194
|
|
ABCA4
|
ATP-binding cassette, sub-family A (ABC1), member 4
|
2.05717
|
|
SFTPB
|
surfactant protein B
|
2.04349
|
|
MICALL2
|
MICAL-like 2
|
2.03978
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.68247
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-7.63441
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-6.65801
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.55851
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.3822
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.11539
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.00702
|
|
TLR4
|
toll-like receptor 4
|
-3.99449
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.77517
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.7034
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-3.43133
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.77947
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.75581
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.59203
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
-2.57141
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.41913
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.41896
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.16267
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.16045
|
|
UCHL1
|
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
|
-2.15886
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.13508
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.10944
|
|
TRIM32
|
tripartite motif containing 32
|
-2.10016
|
|
WDR47
|
WD repeat domain 47
|
-2.09141
|
|
RNF167
|
ring finger protein 167
|
-2.06409
|
|
CTSG
|
cathepsin G
|
-2.04886
|
