CRCGN014_HEPG2_3H:A10 Gene Set
Genes
50 genes differentially expressed following the CRCGN014_HEPG2_3H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
6.29786
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.56051
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
4.24949
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.22222
|
|
PLSCR1
|
phospholipid scramblase 1
|
4.169
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.00708
|
|
E2F2
|
E2F transcription factor 2
|
4.00388
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.8856
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.10272
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.98426
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.88764
|
|
EIF2D
|
eukaryotic translation initiation factor 2D
|
2.77917
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.75641
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.74574
|
|
NUP133
|
nucleoporin 133kDa
|
2.59872
|
|
BMP4
|
bone morphogenetic protein 4
|
2.59347
|
|
PMM2
|
phosphomannomutase 2
|
2.50523
|
|
TLK2
|
tousled-like kinase 2
|
2.35192
|
|
PRR15L
|
proline rich 15-like
|
2.34617
|
|
GALR3
|
galanin receptor 3
|
2.27846
|
|
MEST
|
mesoderm specific transcript
|
2.13547
|
|
SFTPB
|
surfactant protein B
|
2.04507
|
|
CTSL
|
cathepsin L
|
2.04038
|
|
CPQ
|
carboxypeptidase Q
|
2.01446
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.09363
|
|
ZNF586
|
zinc finger protein 586
|
-5.00647
|
|
LDHD
|
lactate dehydrogenase D
|
-4.73332
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-4.62286
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.54533
|
|
GOLT1B
|
golgi transport 1B
|
-4.28604
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.06328
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.83715
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.81615
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.70868
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.63292
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.34925
|
|
RHEB
|
Ras homolog enriched in brain
|
-3.08339
|
|
SNX11
|
sorting nexin 11
|
-3.08099
|
|
LBHD1
|
LBH domain containing 1
|
-2.58921
|
|
PAAF1
|
proteasomal ATPase-associated factor 1
|
-2.39094
|
|
WDR7
|
WD repeat domain 7
|
-2.39017
|
|
CAB39
|
calcium binding protein 39
|
-2.36407
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.33293
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.21227
|
|
DMAP1
|
DNA methyltransferase 1 associated protein 1
|
-2.17297
|
|
NVL
|
nuclear VCP-like
|
-2.13734
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.11456
|
|
HSPA12A
|
heat shock 70kDa protein 12A
|
-2.09936
|
|
SCAND1
|
SCAN domain containing 1
|
-2.04336
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.02625
|
