| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | metronidazole 41.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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95 genes differentially expressed following the CRCGN014_HEPG2_3H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 7.78493 |
| PMM2 | phosphomannomutase 2 | 5.60298 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.9017 |
| CBR3 | carbonyl reductase 3 | 4.88531 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.42786 |
| UBQLN2 | ubiquilin 2 | 4.33177 |
| MAP7 | microtubule-associated protein 7 | 3.89131 |
| CEP57 | centrosomal protein 57kDa | 3.86003 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 3.50147 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.03997 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.92698 |
| BLCAP | bladder cancer associated protein | 2.77726 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 2.68891 |
| KIF20A | kinesin family member 20A | 2.62985 |
| MYL11 | myosin light chain 11 | 2.53595 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.52105 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.51888 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 2.42215 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.40157 |
| CASC3 | cancer susceptibility candidate 3 | 2.38911 |
| CHN1 | chimerin 1 | 2.36103 |
| NOSIP | nitric oxide synthase interacting protein | 2.32151 |
| CCNA2 | cyclin A2 | 2.3012 |
| SNX6 | sorting nexin 6 | 2.29917 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.29528 |
| INTS11 | integrator complex subunit 11 | 2.27412 |
| RACGAP1 | Rac GTPase activating protein 1 | 2.26226 |
| TRAM2 | translocation associated membrane protein 2 | 2.23921 |
| SAA2 | serum amyloid A2 | 2.2073 |
| TNNC2 | troponin C type 2 (fast) | 2.20411 |
| IL7 | interleukin 7 | 2.20245 |
| GRSF1 | G-rich RNA sequence binding factor 1 | 2.19975 |
| GRAMD4 | GRAM domain containing 4 | 2.17985 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.1617 |
| CDK19 | cyclin-dependent kinase 19 | 2.14656 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.14336 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 2.13477 |
| DBR1 | debranching RNA lariats 1 | 2.13269 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 2.12638 |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 | 2.11842 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 2.1149 |
| HEBP1 | heme binding protein 1 | 2.11338 |
| PLSCR3 | phospholipid scramblase 3 | 2.10039 |
| LAP3 | leucine aminopeptidase 3 | 2.09251 |
| ZNF263 | zinc finger protein 263 | 2.09173 |
| S100A12 | S100 calcium binding protein A12 | 2.07477 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 | 2.07228 |
| GK | glycerol kinase | 2.06744 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.06164 |
| SPAG7 | sperm associated antigen 7 | 2.05483 |
| STOM | stomatin | 2.03001 |
| CYB5R1 | cytochrome b5 reductase 1 | 2.01663 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) | 2.00592 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.33722 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.45862 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.07608 |
| LDHD | lactate dehydrogenase D | -4.9805 |
| CCNB2 | cyclin B2 | -4.69929 |
| HAT1 | histone acetyltransferase 1 | -4.62952 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -4.46796 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -4.46123 |
| WASHC4 | WASH complex subunit 4 | -4.22199 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.02727 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.91153 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) | -2.86784 |
| CCNH | cyclin H | -2.82716 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.52979 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.45575 |
| SOX17 | SRY (sex determining region Y)-box 17 | -2.40042 |
| FRZB | frizzled-related protein | -2.3895 |
| RAP1B | RAP1B, member of RAS oncogene family | -2.36558 |
| NISCH | nischarin | -2.36394 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | -2.35682 |
| TBC1D31 | TBC1 domain family, member 31 | -2.33711 |
| SLC35F2 | solute carrier family 35, member F2 | -2.2697 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -2.25181 |
| CCDC181 | coiled-coil domain containing 181 | -2.25015 |
| PNMA8A | PNMA family member 8A | -2.24526 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -2.24345 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.22375 |
| CLTB | clathrin, light chain B | -2.20468 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.19132 |
| SPAG4 | sperm associated antigen 4 | -2.17943 |
| VPREB3 | pre-B lymphocyte 3 | -2.17755 |
| CSK | c-src tyrosine kinase | -2.1521 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.14299 |
| IL5 | interleukin 5 | -2.10265 |
| FAM200C | family with sequence similarity 200 member C | -2.10084 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.05581 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -2.04968 |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | -2.04087 |
| TNN | tenascin N | -2.03061 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -2.02924 |
| TXNDC9 | thioredoxin domain containing 9 | -2.02869 |
| PCYOX1L | prenylcysteine oxidase 1 like | -2.02474 |
