CRCGN014_HEPG2_3H:A14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phthalic anhydride 39.8 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

45 genes differentially expressed following the CRCGN014_HEPG2_3H:A14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CARMIL1 capping protein regulator and myosin 1 linker 1 5.98597
MAP7 microtubule-associated protein 7 5.60762
UBQLN2 ubiquilin 2 4.60538
CYCS cytochrome c, somatic 4.40562
CIAO3 cytosolic iron-sulfur assembly component 3 4.0443
STK10 serine/threonine kinase 10 4.04409
PPARG peroxisome proliferator-activated receptor gamma 3.7096
DIPK1A divergent protein kinase domain 1A 3.58205
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.88527
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.76622
SKIC8 SKI8 subunit of superkiller complex 2.74575
KIF14 kinesin family member 14 2.45877
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.44595
CCNF cyclin F 2.3855
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.34991
NOSIP nitric oxide synthase interacting protein 2.34985
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.28377
SAA2 serum amyloid A2 2.27902
PRKCG protein kinase C, gamma 2.26336
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.23235
CHN1 chimerin 1 2.19396
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.13965
NDC80 NDC80 kinetochore complex component 2.13946
KLHL9 kelch-like family member 9 2.12933
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.09306
PXMP2 peroxisomal membrane protein 2, 22kDa 2.09205
KLHDC2 kelch domain containing 2 2.06327
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.05042
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.03392
CKMT1A creatine kinase, mitochondrial 1A 2.02468

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.43367
ADI1 acireductone dioxygenase 1 -3.99889
CCNB2 cyclin B2 -3.75522
FASTKD5 FAST kinase domains 5 -3.40857
ACAA1 acetyl-CoA acyltransferase 1 -2.8434
HMG20B high mobility group 20B -2.84162
OXA1L oxidase (cytochrome c) assembly 1-like -2.76882
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.75197
TXNDC9 thioredoxin domain containing 9 -2.74989
COG7 component of oligomeric golgi complex 7 -2.38875
TCEAL4 transcription elongation factor A (SII)-like 4 -2.36472
SNX11 sorting nexin 11 -2.13236
HEATR1 HEAT repeat containing 1 -2.10659
EIF5 eukaryotic translation initiation factor 5 -2.05234
CSK c-src tyrosine kinase -2.038